Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine

The aim was to investigate the vector-cardiographic effects in patients submitted to dental extraction under local anesthesia. Twenty-one patients aged 36.6 ± 12.4 years with a clinical and radiographic indication of mandibular or maxillary tooth extraction were enrolled. The intervention was a loca...

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Main Authors: Christoph Pökel, Antina Schulze, Martin Busse
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2024/8610423
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author Christoph Pökel
Antina Schulze
Martin Busse
author_facet Christoph Pökel
Antina Schulze
Martin Busse
author_sort Christoph Pökel
collection DOAJ
description The aim was to investigate the vector-cardiographic effects in patients submitted to dental extraction under local anesthesia. Twenty-one patients aged 36.6 ± 12.4 years with a clinical and radiographic indication of mandibular or maxillary tooth extraction were enrolled. The intervention was a local or mandibular nerve block anesthesia with 4% articaine hydrochloride containing epinephrine (1 : 100,000; 40 mg/ml + 10 μg/ml). Blood pressure (BP), heart rate (HR), pulse wave transit time, and vector-cardiography data were recorded throughout 3 min before and 5 min after injection. QRS- and T-wave area under the curve (QRSAUC/TAUC) were calculated from the X/Y/Z QRS-vector or T-vector. T-wave amplitude (TAM), TAUC values, and diastolic BP decreased, and HR significantly increased 4 min after injection. A transient moderate HR drop and a corresponding small increase in TAM and TAUC immediately after the injection procedure may be explained by a decreased sympathetic tone due to psychological relief. In dental anesthesia, the systemic epinephrine effects are represented by a decrease in TAUC. These effects are most pronounced in the X- and Y-leads. The 3D determination of vector planes or amplitudes is a simple method to register the sympathetic tone in local anesthesia independently of possible effects on T-wave characteristics in single leads. In conclusion, T-wave determination may help to detect even small increases in systemic adrenaline concentration in case of accidental intravascular injection. At the same time, full rhythm and spatial ischemia control is provided.
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spelling doaj-art-fe8ab74ad65a42688feb85ae9a8dd04e2025-02-03T01:30:21ZengWileyInternational Journal of Dentistry1687-87362024-01-01202410.1155/2024/8610423Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with EpinephrineChristoph Pökel0Antina Schulze1Martin Busse2General Outpatient Clinic of Sports MedicineDepartment of Sports DentistryGeneral Outpatient Clinic of Sports MedicineThe aim was to investigate the vector-cardiographic effects in patients submitted to dental extraction under local anesthesia. Twenty-one patients aged 36.6 ± 12.4 years with a clinical and radiographic indication of mandibular or maxillary tooth extraction were enrolled. The intervention was a local or mandibular nerve block anesthesia with 4% articaine hydrochloride containing epinephrine (1 : 100,000; 40 mg/ml + 10 μg/ml). Blood pressure (BP), heart rate (HR), pulse wave transit time, and vector-cardiography data were recorded throughout 3 min before and 5 min after injection. QRS- and T-wave area under the curve (QRSAUC/TAUC) were calculated from the X/Y/Z QRS-vector or T-vector. T-wave amplitude (TAM), TAUC values, and diastolic BP decreased, and HR significantly increased 4 min after injection. A transient moderate HR drop and a corresponding small increase in TAM and TAUC immediately after the injection procedure may be explained by a decreased sympathetic tone due to psychological relief. In dental anesthesia, the systemic epinephrine effects are represented by a decrease in TAUC. These effects are most pronounced in the X- and Y-leads. The 3D determination of vector planes or amplitudes is a simple method to register the sympathetic tone in local anesthesia independently of possible effects on T-wave characteristics in single leads. In conclusion, T-wave determination may help to detect even small increases in systemic adrenaline concentration in case of accidental intravascular injection. At the same time, full rhythm and spatial ischemia control is provided.http://dx.doi.org/10.1155/2024/8610423
spellingShingle Christoph Pökel
Antina Schulze
Martin Busse
Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine
International Journal of Dentistry
title Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine
title_full Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine
title_fullStr Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine
title_full_unstemmed Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine
title_short Cardiovascular and Vector-Cardiographic Effects of Articaine Anesthesia with Epinephrine
title_sort cardiovascular and vector cardiographic effects of articaine anesthesia with epinephrine
url http://dx.doi.org/10.1155/2024/8610423
work_keys_str_mv AT christophpokel cardiovascularandvectorcardiographiceffectsofarticaineanesthesiawithepinephrine
AT antinaschulze cardiovascularandvectorcardiographiceffectsofarticaineanesthesiawithepinephrine
AT martinbusse cardiovascularandvectorcardiographiceffectsofarticaineanesthesiawithepinephrine