High refractive index silicone gels for simultaneous total internal reflection fluorescence and traction force microscopy of adherent cells.
Substrate rigidity profoundly impacts cellular behaviors such as migration, gene expression, and cell fate. Total Internal Reflection Fluorescence (TIRF) microscopy enables selective visualization of the dynamics of substrate adhesions, vesicle trafficking, and biochemical signaling at the cell-subs...
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| Main Authors: | Edgar Gutierrez, Eugene Tkachenko, Achim Besser, Prithu Sundd, Klaus Ley, Gaudenz Danuser, Mark H Ginsberg, Alex Groisman |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0023807&type=printable |
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