M2 macrophage-derived exosome-modified bioprosthetic heart valves with enhanced anti-inflammatory, anticoagulant and anticalcification properties

Glutaraldehyde (Glut) cross-linked bioprosthetic heart valves (BHVs) have shown great performance in the replacement treatment of severe valvular heart diseases in recent years due to the rapid development of transcatheter aortic valve replacement (TAVR) and the aging population. However, the durabi...

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Bibliographic Details
Main Authors: Jingruo Chen, Shufen Li, Xiaoting Chen, Tianyi Qu, Ming Chen, Zheng Chai, Weihua Zhuang, Wenchuang (Walter) Hu, Mao Chen
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127525004381
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