A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss
Osteoporosis is a multifactorial skeletal disorder characterized by decreased bone mass and deteriorated microarchitecture that lead to increased risk of fracture. The disuse osteoporosis refers to bone mass decrements under conditions of decreased mechanical loading, including decreased ground for...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Journal of Osteoporosis |
| Online Access: | http://dx.doi.org/10.4061/2011/293808 |
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| _version_ | 1832552267333500928 |
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| author | Roy Yuen-chi Lau Xia Guo |
| author_facet | Roy Yuen-chi Lau Xia Guo |
| author_sort | Roy Yuen-chi Lau |
| collection | DOAJ |
| description | Osteoporosis is a multifactorial skeletal disorder characterized by decreased bone mass and deteriorated microarchitecture that lead to increased risk of fracture. The disuse osteoporosis refers to bone mass decrements under conditions of decreased mechanical loading, including decreased ground force reaction, muscular contraction, and microgravity-related bone loss in astronauts after space flights. Although there are many effective treatments available for primary osteoporosis, there is a lack of effective treatments for disuse osteoporosis. This is because that the aetiology, pathophysiology, and resultant pathology of disuse osteoporosis differ from those of primary osteoporosis. The objective of this paper is to examine the unique pathology and underlying pathophysiology of disuse osteoporosis. |
| format | Article |
| id | doaj-art-fe15d49da5a343aba1a85ab03e733616 |
| institution | Kabale University |
| issn | 2042-0064 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Osteoporosis |
| spelling | doaj-art-fe15d49da5a343aba1a85ab03e7336162025-02-03T05:59:14ZengWileyJournal of Osteoporosis2042-00642011-01-01201110.4061/2011/293808293808A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone LossRoy Yuen-chi Lau0Xia Guo1Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong KongDepartment of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong KongOsteoporosis is a multifactorial skeletal disorder characterized by decreased bone mass and deteriorated microarchitecture that lead to increased risk of fracture. The disuse osteoporosis refers to bone mass decrements under conditions of decreased mechanical loading, including decreased ground force reaction, muscular contraction, and microgravity-related bone loss in astronauts after space flights. Although there are many effective treatments available for primary osteoporosis, there is a lack of effective treatments for disuse osteoporosis. This is because that the aetiology, pathophysiology, and resultant pathology of disuse osteoporosis differ from those of primary osteoporosis. The objective of this paper is to examine the unique pathology and underlying pathophysiology of disuse osteoporosis.http://dx.doi.org/10.4061/2011/293808 |
| spellingShingle | Roy Yuen-chi Lau Xia Guo A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss Journal of Osteoporosis |
| title | A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss |
| title_full | A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss |
| title_fullStr | A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss |
| title_full_unstemmed | A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss |
| title_short | A Review on Current Osteoporosis Research: With Special Focus on Disuse Bone Loss |
| title_sort | review on current osteoporosis research with special focus on disuse bone loss |
| url | http://dx.doi.org/10.4061/2011/293808 |
| work_keys_str_mv | AT royyuenchilau areviewoncurrentosteoporosisresearchwithspecialfocusondisuseboneloss AT xiaguo areviewoncurrentosteoporosisresearchwithspecialfocusondisuseboneloss AT royyuenchilau reviewoncurrentosteoporosisresearchwithspecialfocusondisuseboneloss AT xiaguo reviewoncurrentosteoporosisresearchwithspecialfocusondisuseboneloss |