3D-printed titanium dioxide-reinforced calcium silicate composite scaffold promotes efficient bone defect repair through activation of osteogenic and angiogenic differentiation

3D-printed titanium dioxide-reinforced calcium silicate composite scaffold promotes efficient bone defect repair through activation of osteogenic and angiogenic differentiation

Addressing the challenges of insufficient mechanical strength, high fragility, and rapid degradation in calcium silicate (CS) 3D-printed bone regeneration scaffolds and acknowledging the necessity to enhance performance of CS in bone and vascular regeneration, this study innovatively presents a tita...

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Bibliographic Details
Main Authors: Zhiqiang Huang, Xinyi Wang, Zhaowenbin Zhang, Bin Yu, Suqi Wang, Xiaoting Chen, Yi Zhang, Jin Yang, Zhen Zeng, Zhihong Dong
Format: Article
Language:English
Published: Elsevier 2025-07-01
Series:Materials & Design
Subjects:
Titanium dioxide
Calcium silicate
3D-printed scaffold
Bone defect repair
BMSCs
HUVECs
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127525005866
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