Oxy-inflammation in hyperbaric oxygen therapy applications

Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined...

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Main Authors: Gerardo Bosco, Andrea Brizzolari, Matteo Paganini, Enrico Camporesi, Alessandra Vezzoli, Simona Mrakic-Sposta
Format: Article
Language:English
Published: PAGEPress Publications 2025-01-01
Series:European Journal of Translational Myology
Online Access:https://www.pagepressjournals.org/bam/article/view/12783
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author Gerardo Bosco
Andrea Brizzolari
Matteo Paganini
Enrico Camporesi
Alessandra Vezzoli
Simona Mrakic-Sposta
author_facet Gerardo Bosco
Andrea Brizzolari
Matteo Paganini
Enrico Camporesi
Alessandra Vezzoli
Simona Mrakic-Sposta
author_sort Gerardo Bosco
collection DOAJ
description Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. HBOT relies on increasing the inspired O2 fraction (fiO2) and elevating the partial pressure of O2 (pO2). O2 is typically administered at pressures between 1.5 and 3.0 ATA for 60 to 120 minutes, depending on the clinical presentation. Currently, there are 15 indications for HBOT approved by the Undersea and Hyperbaric Medicine Society, categorized into three groups: emergency medicine, wound healing acceleration, and antimicrobial effects. The present narrative review aims to elucidate the mechanisms action underlying HBOT, particularly oxy-inflammation, in various pathologies within these categories.
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institution Kabale University
issn 2037-7452
2037-7460
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publishDate 2025-01-01
publisher PAGEPress Publications
record_format Article
series European Journal of Translational Myology
spelling doaj-art-fdf63a7839b14b3185d5f9ebe782d2972025-01-21T10:55:48ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602025-01-0110.4081/ejtm.2025.12783Oxy-inflammation in hyperbaric oxygen therapy applicationsGerardo Bosco0Andrea Brizzolari1Matteo Paganini2Enrico Camporesi3Alessandra Vezzoli4Simona Mrakic-Sposta5Department of Biomedical Sciences, University of Padua, PaduaDepartment of Biomedical Sciences, University of Padua, PaduaDepartment of Biomedical Sciences, University of Padua, PaduaTEAM Health Anaesthesia, Tampa General Hospital, Tampa, FloridaInstitute of Clinical Physiology, National Research Council (IFC-CNR), MilanInstitute of Clinical Physiology, National Research Council (IFC-CNR), Milan Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. HBOT relies on increasing the inspired O2 fraction (fiO2) and elevating the partial pressure of O2 (pO2). O2 is typically administered at pressures between 1.5 and 3.0 ATA for 60 to 120 minutes, depending on the clinical presentation. Currently, there are 15 indications for HBOT approved by the Undersea and Hyperbaric Medicine Society, categorized into three groups: emergency medicine, wound healing acceleration, and antimicrobial effects. The present narrative review aims to elucidate the mechanisms action underlying HBOT, particularly oxy-inflammation, in various pathologies within these categories. https://www.pagepressjournals.org/bam/article/view/12783
spellingShingle Gerardo Bosco
Andrea Brizzolari
Matteo Paganini
Enrico Camporesi
Alessandra Vezzoli
Simona Mrakic-Sposta
Oxy-inflammation in hyperbaric oxygen therapy applications
European Journal of Translational Myology
title Oxy-inflammation in hyperbaric oxygen therapy applications
title_full Oxy-inflammation in hyperbaric oxygen therapy applications
title_fullStr Oxy-inflammation in hyperbaric oxygen therapy applications
title_full_unstemmed Oxy-inflammation in hyperbaric oxygen therapy applications
title_short Oxy-inflammation in hyperbaric oxygen therapy applications
title_sort oxy inflammation in hyperbaric oxygen therapy applications
url https://www.pagepressjournals.org/bam/article/view/12783
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AT enricocamporesi oxyinflammationinhyperbaricoxygentherapyapplications
AT alessandravezzoli oxyinflammationinhyperbaricoxygentherapyapplications
AT simonamrakicsposta oxyinflammationinhyperbaricoxygentherapyapplications