Oxy-inflammation in hyperbaric oxygen therapy applications
Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined...
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PAGEPress Publications
2025-01-01
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Series: | European Journal of Translational Myology |
Online Access: | https://www.pagepressjournals.org/bam/article/view/12783 |
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author | Gerardo Bosco Andrea Brizzolari Matteo Paganini Enrico Camporesi Alessandra Vezzoli Simona Mrakic-Sposta |
author_facet | Gerardo Bosco Andrea Brizzolari Matteo Paganini Enrico Camporesi Alessandra Vezzoli Simona Mrakic-Sposta |
author_sort | Gerardo Bosco |
collection | DOAJ |
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Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. HBOT relies on increasing the inspired O2 fraction (fiO2) and elevating the partial pressure of O2 (pO2). O2 is typically administered at pressures between 1.5 and 3.0 ATA for 60 to 120 minutes, depending on the clinical presentation. Currently, there are 15 indications for HBOT approved by the Undersea and Hyperbaric Medicine Society, categorized into three groups: emergency medicine, wound healing acceleration, and antimicrobial effects. The present narrative review aims to elucidate the mechanisms action underlying HBOT, particularly oxy-inflammation, in various pathologies within these categories.
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format | Article |
id | doaj-art-fdf63a7839b14b3185d5f9ebe782d297 |
institution | Kabale University |
issn | 2037-7452 2037-7460 |
language | English |
publishDate | 2025-01-01 |
publisher | PAGEPress Publications |
record_format | Article |
series | European Journal of Translational Myology |
spelling | doaj-art-fdf63a7839b14b3185d5f9ebe782d2972025-01-21T10:55:48ZengPAGEPress PublicationsEuropean Journal of Translational Myology2037-74522037-74602025-01-0110.4081/ejtm.2025.12783Oxy-inflammation in hyperbaric oxygen therapy applicationsGerardo Bosco0Andrea Brizzolari1Matteo Paganini2Enrico Camporesi3Alessandra Vezzoli4Simona Mrakic-Sposta5Department of Biomedical Sciences, University of Padua, PaduaDepartment of Biomedical Sciences, University of Padua, PaduaDepartment of Biomedical Sciences, University of Padua, PaduaTEAM Health Anaesthesia, Tampa General Hospital, Tampa, FloridaInstitute of Clinical Physiology, National Research Council (IFC-CNR), MilanInstitute of Clinical Physiology, National Research Council (IFC-CNR), Milan Hyperbaric oxygen therapy (HBOT) is a non-invasive method of O2 delivery that induces systemic hyperoxia. Hyperbaric chamber consists of a pressure vessel and a compressed breathing gas supply, which can regulate internal pressure. The chamber delivers 100% O2 to patients according to predetermined protocols and is monitored by trained personnel. HBOT relies on increasing the inspired O2 fraction (fiO2) and elevating the partial pressure of O2 (pO2). O2 is typically administered at pressures between 1.5 and 3.0 ATA for 60 to 120 minutes, depending on the clinical presentation. Currently, there are 15 indications for HBOT approved by the Undersea and Hyperbaric Medicine Society, categorized into three groups: emergency medicine, wound healing acceleration, and antimicrobial effects. The present narrative review aims to elucidate the mechanisms action underlying HBOT, particularly oxy-inflammation, in various pathologies within these categories. https://www.pagepressjournals.org/bam/article/view/12783 |
spellingShingle | Gerardo Bosco Andrea Brizzolari Matteo Paganini Enrico Camporesi Alessandra Vezzoli Simona Mrakic-Sposta Oxy-inflammation in hyperbaric oxygen therapy applications European Journal of Translational Myology |
title | Oxy-inflammation in hyperbaric oxygen therapy applications |
title_full | Oxy-inflammation in hyperbaric oxygen therapy applications |
title_fullStr | Oxy-inflammation in hyperbaric oxygen therapy applications |
title_full_unstemmed | Oxy-inflammation in hyperbaric oxygen therapy applications |
title_short | Oxy-inflammation in hyperbaric oxygen therapy applications |
title_sort | oxy inflammation in hyperbaric oxygen therapy applications |
url | https://www.pagepressjournals.org/bam/article/view/12783 |
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