Unexpected renal influence on isavuconazole trough concentrations: two case reports and literature review
Isavuconazole (ISA) is a first-line treatment for invasive aspergillosis, with routine therapeutic drug monitoring (TDM) typically deemed unnecessary. Although the drug label and prior studies suggest renal function does not affect ISA pharmacokinetics, our findings in two high-risk patients challen...
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| Main Authors: | Hui Li, Xiaoshuang He, Qiuya Lu, Ling Wang, Jieling Jiang, Wenhui Gao, Lining Wang, Jiong Hu, Jie Fang, Xiaolan Bian |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Medicine |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1625697/full |
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