Brachytherapy for Prostate Cancer: A Systematic Review

Low-dose rate brachytherapy has become a mainstream treatment option for men diagnosed with prostate cancer because of excellent long-term treatment outcomes in low-, intermediate-, and high-risk patients. To a great extend due to patient lead advocacy for minimally invasive treatment options, high-...

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Main Authors: Georgios Koukourakis, Nikolaos Kelekis, Vassilios Armonis, Vassilios Kouloulias
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2009/327945
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author Georgios Koukourakis
Nikolaos Kelekis
Vassilios Armonis
Vassilios Kouloulias
author_facet Georgios Koukourakis
Nikolaos Kelekis
Vassilios Armonis
Vassilios Kouloulias
author_sort Georgios Koukourakis
collection DOAJ
description Low-dose rate brachytherapy has become a mainstream treatment option for men diagnosed with prostate cancer because of excellent long-term treatment outcomes in low-, intermediate-, and high-risk patients. To a great extend due to patient lead advocacy for minimally invasive treatment options, high-quality prostate implants have become widely available in the US, Europe, and Japan. High-dose-rate (HDR) afterloading brachytherapy in the management of localised prostate cancer has practical, physical, and biological advantages over low-dose-rate seed brachytherapy. There are no free live sources used, no risk of source loss, and since the implant is a temporary procedure following discharge no issues with regard to radioprotection use of existing facilities exist. Patients with localized prostate cancer may benefit from high-dose-rate brachytherapy, which may be used alone in certain circumstances or in combination with external-beam radiotherapy in other settings. The purpose of this paper is to present the essentials of brachytherapies techniques along with the most important studies that support their effectiveness in the treatment of prostate cancer.
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institution Kabale University
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spelling doaj-art-fdd16993658a40b09d8748e35111acc12025-02-03T01:00:58ZengWileyAdvances in Urology1687-63691687-63772009-01-01200910.1155/2009/327945327945Brachytherapy for Prostate Cancer: A Systematic ReviewGeorgios Koukourakis0Nikolaos Kelekis1Vassilios Armonis2Vassilios Kouloulias3Radiation Therapy Unit, Second Department of Radiology, University Hospital of Athens “ATTIKON”, Rimini 1 Haidari, 124 64 Athens, GreeceSecond Department of Radiology, University Hospital of Athens “ATTIKON”, Rimini 1 Haidari, 124 64 Athens, Greece6th Oncologic Deparment of IKA, Asopiou 4, Alexandras Avenue, 11474 Athens, GreeceRadiation Therapy Unit, Second Department of Radiology, University Hospital of Athens “ATTIKON”, Rimini 1 Haidari, 124 64 Athens, GreeceLow-dose rate brachytherapy has become a mainstream treatment option for men diagnosed with prostate cancer because of excellent long-term treatment outcomes in low-, intermediate-, and high-risk patients. To a great extend due to patient lead advocacy for minimally invasive treatment options, high-quality prostate implants have become widely available in the US, Europe, and Japan. High-dose-rate (HDR) afterloading brachytherapy in the management of localised prostate cancer has practical, physical, and biological advantages over low-dose-rate seed brachytherapy. There are no free live sources used, no risk of source loss, and since the implant is a temporary procedure following discharge no issues with regard to radioprotection use of existing facilities exist. Patients with localized prostate cancer may benefit from high-dose-rate brachytherapy, which may be used alone in certain circumstances or in combination with external-beam radiotherapy in other settings. The purpose of this paper is to present the essentials of brachytherapies techniques along with the most important studies that support their effectiveness in the treatment of prostate cancer.http://dx.doi.org/10.1155/2009/327945
spellingShingle Georgios Koukourakis
Nikolaos Kelekis
Vassilios Armonis
Vassilios Kouloulias
Brachytherapy for Prostate Cancer: A Systematic Review
Advances in Urology
title Brachytherapy for Prostate Cancer: A Systematic Review
title_full Brachytherapy for Prostate Cancer: A Systematic Review
title_fullStr Brachytherapy for Prostate Cancer: A Systematic Review
title_full_unstemmed Brachytherapy for Prostate Cancer: A Systematic Review
title_short Brachytherapy for Prostate Cancer: A Systematic Review
title_sort brachytherapy for prostate cancer a systematic review
url http://dx.doi.org/10.1155/2009/327945
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