Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50%
To examine if mild carotid stenosis correlates with silent vascular brain changes, we studied a prospective population-based cohort “Men born in 1914.” Data from followups at ages 68 and 81, have been used. Carotid ultrasound was performed at age 81, and cerebral blood flow (CBF) was measured with S...
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| Format: | Article |
| Language: | English |
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Wiley
2012-01-01
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| Series: | International Journal of Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/579531 |
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| author | Arkadiusz Siennicki-Lantz Per Wollmer Sölve Elmståhl |
| author_facet | Arkadiusz Siennicki-Lantz Per Wollmer Sölve Elmståhl |
| author_sort | Arkadiusz Siennicki-Lantz |
| collection | DOAJ |
| description | To examine if mild carotid stenosis correlates with silent vascular brain changes, we studied a prospective population-based cohort “Men born in 1914.” Data from followups at ages 68 and 81, have been used. Carotid ultrasound was performed at age 81, and cerebral blood flow (CBF) was measured with SPECT at age 82. Out of 123 stroke-free patients, carotid stenosis <50% was observed in 94% in the right and 89% in the left internal carotid arteries (ICAs). In these subjects, Peak Systolic Velocities in ICA correlated negatively with CBF in a majority of several brain areas, especially in mesial temporal area. Results were limited to normotensive until their seventies, who developed late-onset hypertension with a subsequent blood pressure, pulse pressure, and ankle-brachial index growth. Elderly with asymptomatic carotid stenosis <50% and peak systolic velocities in ICA 0.7–1.3 m/s, should be offered an intensified pharmacotherapy to prevent stroke or silent cerebrovascular events. |
| format | Article |
| id | doaj-art-fdca7c1ac39d46a2bba1a6a55fcce23f |
| institution | OA Journals |
| issn | 2090-2824 2090-2832 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Vascular Medicine |
| spelling | doaj-art-fdca7c1ac39d46a2bba1a6a55fcce23f2025-08-20T02:22:33ZengWileyInternational Journal of Vascular Medicine2090-28242090-28322012-01-01201210.1155/2012/579531579531Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50%Arkadiusz Siennicki-Lantz0Per Wollmer1Sölve Elmståhl2Division of Geriatric Medicine, Department of Health Sciences, Skane University Hospital in Malmö, Lund University, 205 02 Malmö, SwedenUnit of Clinical Physiology and Nuclear Medicine, Department of Clinical Sciences, Skane University Hospital in Malmö, Lund University, 205 02 Malmö, SwedenDivision of Geriatric Medicine, Department of Health Sciences, Skane University Hospital in Malmö, Lund University, 205 02 Malmö, SwedenTo examine if mild carotid stenosis correlates with silent vascular brain changes, we studied a prospective population-based cohort “Men born in 1914.” Data from followups at ages 68 and 81, have been used. Carotid ultrasound was performed at age 81, and cerebral blood flow (CBF) was measured with SPECT at age 82. Out of 123 stroke-free patients, carotid stenosis <50% was observed in 94% in the right and 89% in the left internal carotid arteries (ICAs). In these subjects, Peak Systolic Velocities in ICA correlated negatively with CBF in a majority of several brain areas, especially in mesial temporal area. Results were limited to normotensive until their seventies, who developed late-onset hypertension with a subsequent blood pressure, pulse pressure, and ankle-brachial index growth. Elderly with asymptomatic carotid stenosis <50% and peak systolic velocities in ICA 0.7–1.3 m/s, should be offered an intensified pharmacotherapy to prevent stroke or silent cerebrovascular events.http://dx.doi.org/10.1155/2012/579531 |
| spellingShingle | Arkadiusz Siennicki-Lantz Per Wollmer Sölve Elmståhl Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50% International Journal of Vascular Medicine |
| title | Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50% |
| title_full | Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50% |
| title_fullStr | Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50% |
| title_full_unstemmed | Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50% |
| title_short | Carotid Velocities Determine Cerebral Blood Flow Deficits in Elderly Men with Carotid Stenosis <50% |
| title_sort | carotid velocities determine cerebral blood flow deficits in elderly men with carotid stenosis 50 |
| url | http://dx.doi.org/10.1155/2012/579531 |
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