Pre-frailty is associated with higher risk of gastroesophageal reflux disease: a large prospective cohort study

Abstract To investigate the prospective association of frailty status, especially the early stage, with the long-term risk of Gastroesophageal reflux disease (GERD) in a large prospective cohort. We included participants who were free of GERD and cancer at baseline and use of aspirin and non-steroid...

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Bibliographic Details
Main Authors: Lei Peng, Xueqin Li, Jinfeng Qi, Yangang Shan, Liming Zhang, Zhenqing Yang, Xucheng Wu, George O. Agogo, Zuyun Liu, Genxiang Mao, Honglei Wu
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
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Online Access:https://doi.org/10.1038/s41598-025-93114-1
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