Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma
The aim of this study was to investigate the feasibility of the 4-week IgE/baseline IgE ratio and tryptase to predict the clinical efficacy of omalizumab in the treatment of pediatric moderate-to-severe asthma.
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-05-01
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| Series: | Open Medicine |
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| Online Access: | https://doi.org/10.1515/med-2025-1176 |
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| _version_ | 1849387262390829056 |
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| author | Lu Min Zhao Jing Zeng Mei Zhu AiMin Li JinFen |
| author_facet | Lu Min Zhao Jing Zeng Mei Zhu AiMin Li JinFen |
| author_sort | Lu Min |
| collection | DOAJ |
| description | The aim of this study was to investigate the feasibility of the 4-week IgE/baseline IgE ratio and tryptase to predict the clinical efficacy of omalizumab in the treatment of pediatric moderate-to-severe asthma. |
| format | Article |
| id | doaj-art-fda3a46b9f4c429dae4d6e7deb7cf9b9 |
| institution | Kabale University |
| issn | 2391-5463 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Medicine |
| spelling | doaj-art-fda3a46b9f4c429dae4d6e7deb7cf9b92025-08-20T03:55:16ZengDe GruyterOpen Medicine2391-54632025-05-01201380610.1515/med-2025-1176Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthmaLu Min0Zhao Jing1Zeng Mei2Zhu AiMin3Li JinFen4Department of Pediatrics, Suzhou Research Center of Medical School, Suzhou Hospital, Affliated Hospital of Medical School, Nanjing University, Suzhou, Jiangsu, 215153, ChinaDepartment of Child Health Care, Ezhou Central Hospital, Ezhou, Hubei, 436000, ChinaDepartment of Emergency Medicine, The General Hospital of Western Theater Command PLA, Chengdu, Sichuan, 610000, ChinaDepartment of Pediatrics, The 940th Hospital of Joint Logistic Support Force of Chinese People’s Liberation Army, Lanzhou, Gansu, 730050, ChinaDepartment of Pediatrics, The Fourth Affiliated Hospital of Soochow University, No.9, Chongwen Road, Suzhou Industrial Park, Suzhou, Jiangsu, 215000, ChinaThe aim of this study was to investigate the feasibility of the 4-week IgE/baseline IgE ratio and tryptase to predict the clinical efficacy of omalizumab in the treatment of pediatric moderate-to-severe asthma.https://doi.org/10.1515/med-2025-1176serum igetryptaseomalizumabasthmaefficacy |
| spellingShingle | Lu Min Zhao Jing Zeng Mei Zhu AiMin Li JinFen Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma Open Medicine serum ige tryptase omalizumab asthma efficacy |
| title | Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma |
| title_full | Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma |
| title_fullStr | Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma |
| title_full_unstemmed | Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma |
| title_short | Four-week IgE/baseline IgE ratio combined with tryptase predicts clinical outcome in omalizumab-treated children with moderate-to-severe asthma |
| title_sort | four week ige baseline ige ratio combined with tryptase predicts clinical outcome in omalizumab treated children with moderate to severe asthma |
| topic | serum ige tryptase omalizumab asthma efficacy |
| url | https://doi.org/10.1515/med-2025-1176 |
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