Comparative Effectiveness of Darunavir 1,200 mg Daily and Approved Dosing Strategies for Protease Inhibitor-Experienced Patients
Background. HIV protease inhibitors exhibit concentration-dependent viral inhibition. Higher once daily doses of darunavir boosted with ritonavir (DRV/r) may achieve viral suppression in place of twice daily dosing. International antiretroviral adherence guidelines recommend once daily regimens when...
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Main Authors: | James M. Mikula, Chiu-Bin Hsiao, Joshua R. Sawyer, Qing Ma, Gene D. Morse |
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Format: | Article |
Language: | English |
Published: |
Wiley
2013-01-01
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Series: | AIDS Research and Treatment |
Online Access: | http://dx.doi.org/10.1155/2013/687176 |
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