Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study

Anna Ewa Deda,1 Magdalena Hartman-Petrycka,2 Sławomir Wilczyński2 1Department of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland; 2Department of Basic Biomedical Science, F...

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Main Authors: Deda AE, Hartman-Petrycka M, Wilczyński S
Format: Article
Language:English
Published: Dove Medical Press 2025-01-01
Series:Clinical, Cosmetic and Investigational Dermatology
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Online Access:https://www.dovepress.com/evaluation-of-the-effectiveness-of-using-led-light-combined-with-chrom-peer-reviewed-fulltext-article-CCID
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author Deda AE
Hartman-Petrycka M
Wilczyński S
author_facet Deda AE
Hartman-Petrycka M
Wilczyński S
author_sort Deda AE
collection DOAJ
description Anna Ewa Deda,1 Magdalena Hartman-Petrycka,2 Sławomir Wilczyński2 1Department of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland; 2Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, PolandCorrespondence: Anna Ewa Deda, Department of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jedności 10, Sosnowiec, 41-208, Poland, Email adeda@sum.edu.plPurpose: The aim was to quantitatively evaluate the effectiveness of LED light therapy combined with photoacceptor substances having anti-acne properties in reducing the symptoms of acne vulgaris.Patients and Methods: 15 subjects aged 20 to 24 who suffered from moderate or severe acne lesions. The treatments were performed using a LED device (465– 880 nm). Blue light - 465 nm in combination with red light - 640 nm in pulsed mode and near-infrared light - 880 nm were used in the treatments. Each patient underwent 6 treatments, with intervals between treatments of 7 days. 3D images and biomechanical measurements were performed before first and fourth treatments and 6 weeks after the last. Additionally, photographic documentation was made 7 days after the 6th treatment.Results: The series of treatments significantly influenced the clinical condition of the patients’ skin. The treatments had a statistically significant impact on the intensity of erythema on the left and right cheeks. The hydration of the stratum corneum in all the examined areas of the face changed significantly after the treatments. Greater hydration was achieved six weeks after six treatments compared to the values obtained prior to treatment and after three treatments. The activity of sebaceous glands and, consequently, the amount of sebum on the epidermal surface in all the examined areas of the face changed significantly after the treatments. The treatments had a statistically significant impact on the volume of atrophic scars.Conclusion: Therapy combining LED light with photoacceptor substances is an effective method of reducing the symptoms of acne vulgaris. The treatments lead to a significant reduction in erythema, reduction in the volume of atrophic scars, improvement of skin hydration and regulation of sebum secretion. These effects can be identified quantitatively. Further studies are necessary to confirm the long-term effectiveness and safety of this method.Keywords: phototherapy, sebum, erythema, hydration
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spelling doaj-art-fd9d7208fdff46a3a99eb7dbacc35eea2025-01-23T18:50:32ZengDove Medical PressClinical, Cosmetic and Investigational Dermatology1178-70152025-01-01Volume 1820722199490Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary StudyDeda AEHartman-Petrycka MWilczyński SAnna Ewa Deda,1 Magdalena Hartman-Petrycka,2 Sławomir Wilczyński2 1Department of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, Poland; 2Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Sosnowiec, PolandCorrespondence: Anna Ewa Deda, Department of Practical Cosmetology and Skin Diagnostics, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, Jedności 10, Sosnowiec, 41-208, Poland, Email adeda@sum.edu.plPurpose: The aim was to quantitatively evaluate the effectiveness of LED light therapy combined with photoacceptor substances having anti-acne properties in reducing the symptoms of acne vulgaris.Patients and Methods: 15 subjects aged 20 to 24 who suffered from moderate or severe acne lesions. The treatments were performed using a LED device (465– 880 nm). Blue light - 465 nm in combination with red light - 640 nm in pulsed mode and near-infrared light - 880 nm were used in the treatments. Each patient underwent 6 treatments, with intervals between treatments of 7 days. 3D images and biomechanical measurements were performed before first and fourth treatments and 6 weeks after the last. Additionally, photographic documentation was made 7 days after the 6th treatment.Results: The series of treatments significantly influenced the clinical condition of the patients’ skin. The treatments had a statistically significant impact on the intensity of erythema on the left and right cheeks. The hydration of the stratum corneum in all the examined areas of the face changed significantly after the treatments. Greater hydration was achieved six weeks after six treatments compared to the values obtained prior to treatment and after three treatments. The activity of sebaceous glands and, consequently, the amount of sebum on the epidermal surface in all the examined areas of the face changed significantly after the treatments. The treatments had a statistically significant impact on the volume of atrophic scars.Conclusion: Therapy combining LED light with photoacceptor substances is an effective method of reducing the symptoms of acne vulgaris. The treatments lead to a significant reduction in erythema, reduction in the volume of atrophic scars, improvement of skin hydration and regulation of sebum secretion. These effects can be identified quantitatively. Further studies are necessary to confirm the long-term effectiveness and safety of this method.Keywords: phototherapy, sebum, erythema, hydrationhttps://www.dovepress.com/evaluation-of-the-effectiveness-of-using-led-light-combined-with-chrom-peer-reviewed-fulltext-article-CCIDphototherapysebumerythemahydration
spellingShingle Deda AE
Hartman-Petrycka M
Wilczyński S
Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study
Clinical, Cosmetic and Investigational Dermatology
phototherapy
sebum
erythema
hydration
title Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study
title_full Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study
title_fullStr Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study
title_full_unstemmed Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study
title_short Evaluation of the Effectiveness of Using LED Light Combined With Chromophore Gel in Treating Acne Vulgaris – Preliminary Study
title_sort evaluation of the effectiveness of using led light combined with chromophore gel in treating acne vulgaris ndash preliminary study
topic phototherapy
sebum
erythema
hydration
url https://www.dovepress.com/evaluation-of-the-effectiveness-of-using-led-light-combined-with-chrom-peer-reviewed-fulltext-article-CCID
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AT wilczynskis evaluationoftheeffectivenessofusingledlightcombinedwithchromophoregelintreatingacnevulgarisndashpreliminarystudy