Interchangeable drugs in Peru. A review study
The medicines’ interchangeability represents a necessity in developing countries, because it offers the possibility of accessing lower cost products, it allows to ensure efficacy and safety in pharmacotherapeutic treatments. The study gather researches carried out in the Peruvian state published in...
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| Format: | Article |
| Language: | Spanish |
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Centro Provincial de Información de Ciencias Médicas. Cienfuegos
2023-05-01
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| Series: | Medisur |
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| Online Access: | http://medisur.sld.cu/index.php/medisur/article/view/5690 |
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| author | Ericson Félix Castillo Saavedra Franklin Jhony Julián Méndez Verónica Yamilet Coronel Vega Cecilia Elizabeth Reyes Alfaro Rosa María Salas Sánchez |
| author_facet | Ericson Félix Castillo Saavedra Franklin Jhony Julián Méndez Verónica Yamilet Coronel Vega Cecilia Elizabeth Reyes Alfaro Rosa María Salas Sánchez |
| author_sort | Ericson Félix Castillo Saavedra |
| collection | DOAJ |
| description | The medicines’ interchangeability represents a necessity in developing countries, because it offers the possibility of accessing lower cost products, it allows to ensure efficacy and safety in pharmacotherapeutic treatments. The study gather researches carried out in the Peruvian state published in high-impact databases such as Scielo, Sciencedirect, Scopus and Pubmed. Of the 553 researches found, only 10 articles met the inclusion and exclusion criteria, drugs such as diazepam, prednisone, amoxicillin, doxycycline, fluconazole, phenytoin sodium, alprazolam, amlodipine, carbamazepine sodium, glibenclamide, moxifloxacin and acetylsalicylic acid were identified. All the articles analyzed the dissolution profile by calculating the similarity factor f2, while, in other cases, they estimated parameters such as weight variation, friability, hardness, quantification, content uniformity, and dissolution profile. The results show that 9 drugs included in the study were analyzed by in vitro studies at different pH (1.2; 4.5 and 6.8), and complied with presenting a similarity factor f2 greater than 50. It is concluded that, the interchangeability of medicines in the Peruvian state is still in process, and that, through strategic alliances with the private sector, a greater number of pharmaceutical alternatives could be had in the patient's recovery. |
| format | Article |
| id | doaj-art-fd77291faa7f491d9bfd25b5f5e0d8e6 |
| institution | Kabale University |
| issn | 1727-897X |
| language | Spanish |
| publishDate | 2023-05-01 |
| publisher | Centro Provincial de Información de Ciencias Médicas. Cienfuegos |
| record_format | Article |
| series | Medisur |
| spelling | doaj-art-fd77291faa7f491d9bfd25b5f5e0d8e62025-01-30T21:29:00ZspaCentro Provincial de Información de Ciencias Médicas. CienfuegosMedisur1727-897X2023-05-012136756822306Interchangeable drugs in Peru. A review studyEricson Félix Castillo Saavedra0Franklin Jhony Julián Méndez1Verónica Yamilet Coronel Vega2Cecilia Elizabeth Reyes Alfaro3Rosa María Salas Sánchez4Universidad Nacional de Trujillo. Perú.Universidad Nacional de Trujillo. Perú.Universidad Nacional de Trujillo. Perú.Universidad César Vallejo. Perú.Universidad César Vallejo. Perú.The medicines’ interchangeability represents a necessity in developing countries, because it offers the possibility of accessing lower cost products, it allows to ensure efficacy and safety in pharmacotherapeutic treatments. The study gather researches carried out in the Peruvian state published in high-impact databases such as Scielo, Sciencedirect, Scopus and Pubmed. Of the 553 researches found, only 10 articles met the inclusion and exclusion criteria, drugs such as diazepam, prednisone, amoxicillin, doxycycline, fluconazole, phenytoin sodium, alprazolam, amlodipine, carbamazepine sodium, glibenclamide, moxifloxacin and acetylsalicylic acid were identified. All the articles analyzed the dissolution profile by calculating the similarity factor f2, while, in other cases, they estimated parameters such as weight variation, friability, hardness, quantification, content uniformity, and dissolution profile. The results show that 9 drugs included in the study were analyzed by in vitro studies at different pH (1.2; 4.5 and 6.8), and complied with presenting a similarity factor f2 greater than 50. It is concluded that, the interchangeability of medicines in the Peruvian state is still in process, and that, through strategic alliances with the private sector, a greater number of pharmaceutical alternatives could be had in the patient's recovery.http://medisur.sld.cu/index.php/medisur/article/view/5690preparaciones farmacéuticasequivalencia terapéuticamedicamentos genéricoscalidad de vida |
| spellingShingle | Ericson Félix Castillo Saavedra Franklin Jhony Julián Méndez Verónica Yamilet Coronel Vega Cecilia Elizabeth Reyes Alfaro Rosa María Salas Sánchez Interchangeable drugs in Peru. A review study Medisur preparaciones farmacéuticas equivalencia terapéutica medicamentos genéricos calidad de vida |
| title | Interchangeable drugs in Peru. A review study |
| title_full | Interchangeable drugs in Peru. A review study |
| title_fullStr | Interchangeable drugs in Peru. A review study |
| title_full_unstemmed | Interchangeable drugs in Peru. A review study |
| title_short | Interchangeable drugs in Peru. A review study |
| title_sort | interchangeable drugs in peru a review study |
| topic | preparaciones farmacéuticas equivalencia terapéutica medicamentos genéricos calidad de vida |
| url | http://medisur.sld.cu/index.php/medisur/article/view/5690 |
| work_keys_str_mv | AT ericsonfelixcastillosaavedra interchangeabledrugsinperuareviewstudy AT franklinjhonyjulianmendez interchangeabledrugsinperuareviewstudy AT veronicayamiletcoronelvega interchangeabledrugsinperuareviewstudy AT ceciliaelizabethreyesalfaro interchangeabledrugsinperuareviewstudy AT rosamariasalassanchez interchangeabledrugsinperuareviewstudy |