Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials
Abstract Fatigue is barrier of physical activity participation in adults with chronic conditions. However, physical activity alleviates fatigue symptoms. This systematic review and meta-analysis aimed to (1) synthesise evidence from randomised controlled trials (RCTs) exploring the effects of physic...
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| Format: | Article |
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Nature Portfolio
2023-09-01
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| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-023-41075-8 |
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| author | Ioulia Barakou Kandianos Emmanouil Sakalidis Ulric Sena Abonie Tracy Finch Katie L. Hackett Florentina Johanna Hettinga |
| author_facet | Ioulia Barakou Kandianos Emmanouil Sakalidis Ulric Sena Abonie Tracy Finch Katie L. Hackett Florentina Johanna Hettinga |
| author_sort | Ioulia Barakou |
| collection | DOAJ |
| description | Abstract Fatigue is barrier of physical activity participation in adults with chronic conditions. However, physical activity alleviates fatigue symptoms. This systematic review and meta-analysis aimed to (1) synthesise evidence from randomised controlled trials (RCTs) exploring the effects of physical activity interventions on fatigue reduction and (2) evaluate their effectiveness. Medline/CINAHL/EMBASE/Web of Science and Scopus were searched up to June 24th, 2023. Two reviewers independently conducted study screening and selection (RCTs), extracted data and assessed risk of bias (RoB2). Outcome was the standardised mean difference (SMD) with 95% confidence intervals in fatigue between experimental and control groups. 38 articles met the inclusion criteria. Overall, physical activity interventions moderately reduced fatigue (SMD = 0.70 p < 0.0001). Interventions lasting 2–6 weeks and 16–24 weeks demonstrated the larger effects on fatigue reductions (SMD=0.86, p<0.00001; SMD=1.82, p=0.01, respectively). Interventions with 30-36 sessions showed a large effect on fatigue reduction (SMD = 0.94, p < 0.04). Resistance, aerobic cycling and combination training interventions had a large to moderate effect (SMD= 0.93, p 0.03; SMD = 0.66, p= 0.0005; SMD = 0.76, p = <0.00001, respectively). Small long-term effects were found during follow-up(SMD=0.38, p= 0.002). Notably, both short (2-6 weeks) and longer-term (16-24 weeks) interventions were effective in reducing fatigue. . Physical activity interventions moderately reduced fatigue among adults with chronic conditions. Duration, total sessions, and mode of physical activity were identified as key factors in intervention effectiveness. Further research is needed to explore the impact of physical activity interventions on fatigue. |
| format | Article |
| id | doaj-art-fd625e67cb4344248a4feb14967617c9 |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2023-09-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-fd625e67cb4344248a4feb14967617c92025-01-26T12:35:22ZengNature PortfolioScientific Reports2045-23222023-09-0113112510.1038/s41598-023-41075-8Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trialsIoulia Barakou0Kandianos Emmanouil Sakalidis1Ulric Sena Abonie2Tracy Finch3Katie L. Hackett4Florentina Johanna Hettinga5Department of Nursing, Midwifery & Health, Northumbria UniversityDepartment of Sport Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumberland Building, Northumbria UniversityDepartment of Sport Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumberland Building, Northumbria UniversityDepartment of Nursing, Midwifery & Health, Northumbria UniversityDepartment of Social Work, Education and Community Wellbeing, Northumbria UniversityDepartment of Sport Exercise and Rehabilitation, Faculty of Health and Life Sciences, Northumberland Building, Northumbria UniversityAbstract Fatigue is barrier of physical activity participation in adults with chronic conditions. However, physical activity alleviates fatigue symptoms. This systematic review and meta-analysis aimed to (1) synthesise evidence from randomised controlled trials (RCTs) exploring the effects of physical activity interventions on fatigue reduction and (2) evaluate their effectiveness. Medline/CINAHL/EMBASE/Web of Science and Scopus were searched up to June 24th, 2023. Two reviewers independently conducted study screening and selection (RCTs), extracted data and assessed risk of bias (RoB2). Outcome was the standardised mean difference (SMD) with 95% confidence intervals in fatigue between experimental and control groups. 38 articles met the inclusion criteria. Overall, physical activity interventions moderately reduced fatigue (SMD = 0.70 p < 0.0001). Interventions lasting 2–6 weeks and 16–24 weeks demonstrated the larger effects on fatigue reductions (SMD=0.86, p<0.00001; SMD=1.82, p=0.01, respectively). Interventions with 30-36 sessions showed a large effect on fatigue reduction (SMD = 0.94, p < 0.04). Resistance, aerobic cycling and combination training interventions had a large to moderate effect (SMD= 0.93, p 0.03; SMD = 0.66, p= 0.0005; SMD = 0.76, p = <0.00001, respectively). Small long-term effects were found during follow-up(SMD=0.38, p= 0.002). Notably, both short (2-6 weeks) and longer-term (16-24 weeks) interventions were effective in reducing fatigue. . Physical activity interventions moderately reduced fatigue among adults with chronic conditions. Duration, total sessions, and mode of physical activity were identified as key factors in intervention effectiveness. Further research is needed to explore the impact of physical activity interventions on fatigue.https://doi.org/10.1038/s41598-023-41075-8 |
| spellingShingle | Ioulia Barakou Kandianos Emmanouil Sakalidis Ulric Sena Abonie Tracy Finch Katie L. Hackett Florentina Johanna Hettinga Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials Scientific Reports |
| title | Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials |
| title_full | Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials |
| title_fullStr | Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials |
| title_full_unstemmed | Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials |
| title_short | Effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions: a systematic review and meta-analysis of randomised controlled trials |
| title_sort | effectiveness of physical activity interventions on reducing perceived fatigue among adults with chronic conditions a systematic review and meta analysis of randomised controlled trials |
| url | https://doi.org/10.1038/s41598-023-41075-8 |
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