Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells

The retina is constantly subjected to oxidative stress, which is countered by potent antioxidative systems present in retinal pigment epithelial (RPE) cells. Disruption of these systems leads to the development of age-related macular degeneration. Thioredoxin 2 (Trx2) is a potent antioxidant, which...

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Bibliographic Details
Main Authors: Eriko Sugano, Namie Murayama, Maki Takahashi, Kitako Tabata, Makoto Tamai, Hiroshi Tomita
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Journal of Ophthalmology
Online Access:http://dx.doi.org/10.1155/2013/185825
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