Impeding Quorum Sensing Among the Intestinal Microbiota Impacts the Metastatic Rate of Colorectal Cancer

Impeding Quorum Sensing Among the Intestinal Microbiota Impacts the Metastatic Rate of Colorectal Cancer

ABSTRACT Background The gut microbiota is associated with colorectal cancer (CRC) risk and CRC metastatic potential. However, the role of bacteria in CRC progression and metastasis remains unclear. Aims Here, we hypothesized that microbial communication, mediated through quorum sensing (QS), was a c...

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Bibliographic Details
Main Authors: Matthew Dietz, Travis J. Gates, Rakesh Sikdar, Subbaya Subramanian, Mikael H. Elias, Christopher Staley
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Cancer Medicine
Subjects:
autoinducer
microbiome
organoid
quorum quenching
signaling
Online Access:https://doi.org/10.1002/cam4.71009
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