Methionine Restriction Differentially Modulates Expression of Genes in the Base Excision Repair Pathway in Rat Brain and Liver

Methionine Restriction Differentially Modulates Expression of Genes in the Base Excision Repair Pathway in Rat Brain and Liver

Methionine restriction (MetR) is a dietary intervention that extends mean and maximum life span in rodents, at least in part, by reducing oxidative stress and promoting DNA stability in different tissues. Regarding DNA stability, DNA repair pathways play a critical role, both in the nuclear and mito...

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Bibliographic Details
Main Authors: Ricardo Gredilla, Monica Lopez-Torres, Ines Sanchez-Roman
Format: Article
Language:English
Published: MDPI AG 2025-07-01
Series:Biomolecules
Subjects:
aging
DNA repair
genome stability
oxidative stress
glycosylase
endonuclease
Online Access:https://www.mdpi.com/2218-273X/15/7/969
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