Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG
Attention deficit hyperactivity disorder (ADHD) affects 5-6% of school aged children worldwide. Pharmacological therapy is considered the first-line treatment and methylphenidate (MPH) is considered the first-choice medication. There are two formulations: immediate release (IR) MPH and long-acting (...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Neurology Research International |
| Online Access: | http://dx.doi.org/10.1155/2015/207801 |
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| author | Alfredo Durand-Rivera Efren Alatorre-Miguel Elizabeth Zambrano-Sánchez Celia Reyes-Legorreta |
| author_facet | Alfredo Durand-Rivera Efren Alatorre-Miguel Elizabeth Zambrano-Sánchez Celia Reyes-Legorreta |
| author_sort | Alfredo Durand-Rivera |
| collection | DOAJ |
| description | Attention deficit hyperactivity disorder (ADHD) affects 5-6% of school aged children worldwide. Pharmacological therapy is considered the first-line treatment and methylphenidate (MPH) is considered the first-choice medication. There are two formulations: immediate release (IR) MPH and long-acting (or extended release) formulation (MPH-ER). In this work, we measure the efficacy of treatment for both presentations in one month with Conners’ scales and electroencephalography (EEG). Results. for IR group, in parents and teachers Conners test, all items showed significant differences, towards improvement, except for teachers in perfectionism and emotional instability. For ER group in parent’s Conners test, the items in which there were no significant differences are psychosomatic and emotional instability. For teachers, there were no significant differences in: hyperactivity and perfectionism. Comparing the Conners questionnaires (parents versus teachers) we find significant differences before and after treatment in hyperactivity, perfectionism, psychosomatics, DSM-IV hyperactive-impulsive, and DSM-IV total. In the EEG the Wilcoxon test showed a significant difference (P<0.0001). As we can see, both presentations are suitable for managing the ADHD and have the same effect on the symptomatology and in the EEG. |
| format | Article |
| id | doaj-art-fd370250504546c39067076edc6f688e |
| institution | Kabale University |
| issn | 2090-1852 2090-1860 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Neurology Research International |
| spelling | doaj-art-fd370250504546c39067076edc6f688e2025-02-03T06:10:49ZengWileyNeurology Research International2090-18522090-18602015-01-01201510.1155/2015/207801207801Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEGAlfredo Durand-Rivera0Efren Alatorre-Miguel1Elizabeth Zambrano-Sánchez2Celia Reyes-Legorreta3Laboratorio de Neuroprotección, Servicio de Neurorrehabilitación, Instituto Nacional de Rehabilitación, 14389 México, DF, MexicoLaboratorio de Neuroprotección, Servicio de Neurorrehabilitación, Instituto Nacional de Rehabilitación, 14389 México, DF, MexicoLaboratorio de Neurofisiología Cognitiva, Instituto Nacional de Rehabilitación, 14389 México, DF, MexicoLaboratorio de Neuroprotección, Servicio de Neurorrehabilitación, Instituto Nacional de Rehabilitación, 14389 México, DF, MexicoAttention deficit hyperactivity disorder (ADHD) affects 5-6% of school aged children worldwide. Pharmacological therapy is considered the first-line treatment and methylphenidate (MPH) is considered the first-choice medication. There are two formulations: immediate release (IR) MPH and long-acting (or extended release) formulation (MPH-ER). In this work, we measure the efficacy of treatment for both presentations in one month with Conners’ scales and electroencephalography (EEG). Results. for IR group, in parents and teachers Conners test, all items showed significant differences, towards improvement, except for teachers in perfectionism and emotional instability. For ER group in parent’s Conners test, the items in which there were no significant differences are psychosomatic and emotional instability. For teachers, there were no significant differences in: hyperactivity and perfectionism. Comparing the Conners questionnaires (parents versus teachers) we find significant differences before and after treatment in hyperactivity, perfectionism, psychosomatics, DSM-IV hyperactive-impulsive, and DSM-IV total. In the EEG the Wilcoxon test showed a significant difference (P<0.0001). As we can see, both presentations are suitable for managing the ADHD and have the same effect on the symptomatology and in the EEG.http://dx.doi.org/10.1155/2015/207801 |
| spellingShingle | Alfredo Durand-Rivera Efren Alatorre-Miguel Elizabeth Zambrano-Sánchez Celia Reyes-Legorreta Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG Neurology Research International |
| title | Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG |
| title_full | Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG |
| title_fullStr | Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG |
| title_full_unstemmed | Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG |
| title_short | Methylphenidate Efficacy: Immediate versus Extended Release at Short Term in Mexican Children with ADHD Assessed by Conners Scale and EEG |
| title_sort | methylphenidate efficacy immediate versus extended release at short term in mexican children with adhd assessed by conners scale and eeg |
| url | http://dx.doi.org/10.1155/2015/207801 |
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