Analysis of transcriptomic data reveals the landscape of cholesterol metabolism in prostate cancer and impact of related signature on survival

Analysis of transcriptomic data reveals the landscape of cholesterol metabolism in prostate cancer and impact of related signature on survival

Abstract Background Cholesterol metabolism is essential for the development and progression of prostate cancer (PCa). Our previous study provided a new insight of cholesterol metabolism in the systematic management of PCa. However, the comprehensive role of cholesterol metabolism in PCa remains uncl...

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Bibliographic Details
Main Authors: Jian-Xuan Sun, Ye An, Meng-Yao Xu, Si-Yang Ma, Chen-Qian Liu, Jin-Zhou Xu, Qi-Dong Xia, Shao-Gang Wang
Format: Article
Language:English
Published: Springer 2024-12-01
Series:Discover Oncology
Subjects:
Cholesterol metabolism
Tumor microenvironment
Tumor mutation burden
Prostate cancer
Chemotherapy
Immunotherapy
Online Access:https://doi.org/10.1007/s12672-024-01658-x
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