Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis

Conclusions: Our findings show that the use of low-dose naloxone in combination with opioids can lower the risk of somnolence and coughing, postoperative nausea, and vomiting.

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Main Authors: Benyu Mao, Xian Wang, Xianping Zhang, Min Chen
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/prm/8380502
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author Benyu Mao
Xian Wang
Xianping Zhang
Min Chen
author_facet Benyu Mao
Xian Wang
Xianping Zhang
Min Chen
author_sort Benyu Mao
collection DOAJ
description Conclusions: Our findings show that the use of low-dose naloxone in combination with opioids can lower the risk of somnolence and coughing, postoperative nausea, and vomiting.
format Article
id doaj-art-fcfc7c7ba79947f88aefa93de0e02afd
institution OA Journals
issn 1918-1523
language English
publishDate 2025-01-01
publisher Wiley
record_format Article
series Pain Research and Management
spelling doaj-art-fcfc7c7ba79947f88aefa93de0e02afd2025-08-20T02:00:56ZengWileyPain Research and Management1918-15232025-01-01202510.1155/prm/8380502Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-AnalysisBenyu Mao0Xian Wang1Xianping Zhang2Min Chen3Department of Colorectal SurgeryDepartment of PharmacyDepartment of PharmacyDepartment of PharmacyConclusions: Our findings show that the use of low-dose naloxone in combination with opioids can lower the risk of somnolence and coughing, postoperative nausea, and vomiting.http://dx.doi.org/10.1155/prm/8380502
spellingShingle Benyu Mao
Xian Wang
Xianping Zhang
Min Chen
Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis
Pain Research and Management
title Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis
title_full Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis
title_fullStr Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis
title_full_unstemmed Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis
title_short Opioids With or Without Low-Dose Naloxone During the Perioperative Period: A Systematic Review With Meta-Analysis
title_sort opioids with or without low dose naloxone during the perioperative period a systematic review with meta analysis
url http://dx.doi.org/10.1155/prm/8380502
work_keys_str_mv AT benyumao opioidswithorwithoutlowdosenaloxoneduringtheperioperativeperiodasystematicreviewwithmetaanalysis
AT xianwang opioidswithorwithoutlowdosenaloxoneduringtheperioperativeperiodasystematicreviewwithmetaanalysis
AT xianpingzhang opioidswithorwithoutlowdosenaloxoneduringtheperioperativeperiodasystematicreviewwithmetaanalysis
AT minchen opioidswithorwithoutlowdosenaloxoneduringtheperioperativeperiodasystematicreviewwithmetaanalysis