Feature Selection and Network‐Driven Analyses to Unveil Common RNA Signatures in Colon and Pancreatic KRAS‐Mutant Cancers

Feature Selection and Network‐Driven Analyses to Unveil Common RNA Signatures in Colon and Pancreatic KRAS‐Mutant Cancers

ABSTRACT Background Colon cancer and pancreatic ductal adenocarcinoma are among the most aggressive tumors for which therapeutic options are limited. Both cancers share common features, such as some KRAS pathogenic variants and common epidemiology. The integration of multidimensional datasets by com...

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Bibliographic Details
Main Authors: Katia Pane, Mario Zanfardino, Anna Maria Grimaldi, Ilaria Leone, Silvia Nuzzo, Marco Salvatore, Monica Franzese
Format: Article
Language:English
Published: Wiley 2025-03-01
Series:Cancer Medicine
Subjects:
colon cancer
feature selection
KRAS mutation
network analysis
pancreatic cancer
prognosis
Online Access:https://doi.org/10.1002/cam4.70468
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