Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection
Cryptococcus neoformans is a saprophytic fungus that causes fatal disseminated infections in immunocompromised hosts. Since the onset of the COVID-19 pandemic, multiple cases of secondary viral, bacterial, and fungal infections have been reported in patients after SARS-CoV-2 infection. We describe h...
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2021/5597473 |
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| author | Hebah Ghanem Geetha Sivasubramanian |
| author_facet | Hebah Ghanem Geetha Sivasubramanian |
| author_sort | Hebah Ghanem |
| collection | DOAJ |
| description | Cryptococcus neoformans is a saprophytic fungus that causes fatal disseminated infections in immunocompromised hosts. Since the onset of the COVID-19 pandemic, multiple cases of secondary viral, bacterial, and fungal infections have been reported in patients after SARS-CoV-2 infection. We describe here a case of severe cryptococcal meningitis that developed in a previously healthy patient one week after treatment of SARS-CoV-2 infection with dexamethasone. This case adds to the growing knowledge of emerging secondary infectious complications including opportunistic pathogens after SARS-CoV-2 infection. While few reports allude to depressed T-cell function and lymphopenia due to SARS-CoV-2 infection, further studies are needed to evaluate the effects of this infection and its treatment on the immune system and its contribution to the emergence of secondary opportunistic infections. |
| format | Article |
| id | doaj-art-fcb954f745a14b4684b7245c00f03ddd |
| institution | Kabale University |
| issn | 2090-6625 2090-6633 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-fcb954f745a14b4684b7245c00f03ddd2025-02-03T01:08:51ZengWileyCase Reports in Infectious Diseases2090-66252090-66332021-01-01202110.1155/2021/55974735597473Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 InfectionHebah Ghanem0Geetha Sivasubramanian1Division of Infectious Diseases, Department of Internal Medicine, University of California, San Francisco, Fresno, California, USADivision of Infectious Diseases, Department of Internal Medicine, University of California, San Francisco, Fresno, California, USACryptococcus neoformans is a saprophytic fungus that causes fatal disseminated infections in immunocompromised hosts. Since the onset of the COVID-19 pandemic, multiple cases of secondary viral, bacterial, and fungal infections have been reported in patients after SARS-CoV-2 infection. We describe here a case of severe cryptococcal meningitis that developed in a previously healthy patient one week after treatment of SARS-CoV-2 infection with dexamethasone. This case adds to the growing knowledge of emerging secondary infectious complications including opportunistic pathogens after SARS-CoV-2 infection. While few reports allude to depressed T-cell function and lymphopenia due to SARS-CoV-2 infection, further studies are needed to evaluate the effects of this infection and its treatment on the immune system and its contribution to the emergence of secondary opportunistic infections.http://dx.doi.org/10.1155/2021/5597473 |
| spellingShingle | Hebah Ghanem Geetha Sivasubramanian Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection Case Reports in Infectious Diseases |
| title | Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection |
| title_full | Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection |
| title_fullStr | Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection |
| title_full_unstemmed | Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection |
| title_short | Cryptococcus neoformans Meningoencephalitis in an Immunocompetent Patient after COVID-19 Infection |
| title_sort | cryptococcus neoformans meningoencephalitis in an immunocompetent patient after covid 19 infection |
| url | http://dx.doi.org/10.1155/2021/5597473 |
| work_keys_str_mv | AT hebahghanem cryptococcusneoformansmeningoencephalitisinanimmunocompetentpatientaftercovid19infection AT geethasivasubramanian cryptococcusneoformansmeningoencephalitisinanimmunocompetentpatientaftercovid19infection |