Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment
Systemic lupus erythematosus (SLE) can present with varied neurological manifestations in children. Guillain–Barre syndrome (GBS) as a presenting feature of SLE is quite rare in children. We report a 9-year-old girl who presented with acute motor axonal polyradiculoneuropathy and noticed to have fea...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2019-01-01
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| Series: | Indian Journal of Rheumatology |
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| Online Access: | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=1;spage=74;epage=76;aulast=Reddy |
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| _version_ | 1832569231857680384 |
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| author | Rahul Reddy Anu Punnen Annie Bella Sathish Kumar |
| author_facet | Rahul Reddy Anu Punnen Annie Bella Sathish Kumar |
| author_sort | Rahul Reddy |
| collection | DOAJ |
| description | Systemic lupus erythematosus (SLE) can present with varied neurological manifestations in children. Guillain–Barre syndrome (GBS) as a presenting feature of SLE is quite rare in children. We report a 9-year-old girl who presented with acute motor axonal polyradiculoneuropathy and noticed to have features of SLE. She was initially treated with intravenous immunoglobulins and corticosteroids with partial response. After starting rituximab, she showed dramatic recovery, proving the role of rituximab in GBS refractory to first-line medications in SLE. She remained in remission after 12 months of follow-up. |
| format | Article |
| id | doaj-art-fca150e013e0472da601beba5d98aa36 |
| institution | Kabale University |
| issn | 0973-3698 0973-3701 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Indian Journal of Rheumatology |
| spelling | doaj-art-fca150e013e0472da601beba5d98aa362025-02-02T22:47:44ZengSAGE PublishingIndian Journal of Rheumatology0973-36980973-37012019-01-01141747610.4103/injr.injr_118_18Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatmentRahul ReddyAnu PunnenAnnie BellaSathish KumarSystemic lupus erythematosus (SLE) can present with varied neurological manifestations in children. Guillain–Barre syndrome (GBS) as a presenting feature of SLE is quite rare in children. We report a 9-year-old girl who presented with acute motor axonal polyradiculoneuropathy and noticed to have features of SLE. She was initially treated with intravenous immunoglobulins and corticosteroids with partial response. After starting rituximab, she showed dramatic recovery, proving the role of rituximab in GBS refractory to first-line medications in SLE. She remained in remission after 12 months of follow-up.http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=1;spage=74;epage=76;aulast=ReddyGuillain–Barre syndromerituximabsystemic lupus erythematosus |
| spellingShingle | Rahul Reddy Anu Punnen Annie Bella Sathish Kumar Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment Indian Journal of Rheumatology Guillain–Barre syndrome rituximab systemic lupus erythematosus |
| title | Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment |
| title_full | Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment |
| title_fullStr | Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment |
| title_full_unstemmed | Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment |
| title_short | Guillain–barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it's complete resolution with rituximab treatment |
| title_sort | guillain barre syndrome as a presenting feature of systemic lupus erythematosus in a child and it s complete resolution with rituximab treatment |
| topic | Guillain–Barre syndrome rituximab systemic lupus erythematosus |
| url | http://www.indianjrheumatol.com/article.asp?issn=0973-3698;year=2019;volume=14;issue=1;spage=74;epage=76;aulast=Reddy |
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