Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma

The simultaneous presentation of the Hodgkin lymphoma and multiple myeloma in the absence of prior chemotherapy or radiation is very rare. Here, we discuss a 72-year-old patient who initially presented with generalized pruritis. Workup led to a diagnosis of multiple myeloma which progressed and requ...

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Main Authors: Rekha Chandran, Miklos Simon, Stephen E. Spurgeon
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Hematology
Online Access:http://dx.doi.org/10.1155/2013/398769
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author Rekha Chandran
Miklos Simon
Stephen E. Spurgeon
author_facet Rekha Chandran
Miklos Simon
Stephen E. Spurgeon
author_sort Rekha Chandran
collection DOAJ
description The simultaneous presentation of the Hodgkin lymphoma and multiple myeloma in the absence of prior chemotherapy or radiation is very rare. Here, we discuss a 72-year-old patient who initially presented with generalized pruritis. Workup led to a diagnosis of multiple myeloma which progressed and required treatment. As part of his pretreatment workup, an MRI was performed to evaluate skeletal lesions. This revealed diffuse and bulky adenopathy which was confirmed by PET. A biopsy of an axillary node was consistent with the nodular sclerosing type Hodgkin lymphoma. He was treated with adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) chemotherapy × 6 resulting in complete resolution of his adenopathy and pruritis as well as improvement in his myeloma.
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spelling doaj-art-fc9d3740dd504351a3e74d3ec340a09c2025-02-03T06:11:16ZengWileyCase Reports in Hematology2090-65602090-65792013-01-01201310.1155/2013/398769398769Concurrent Presentation of Hodgkin Lymphoma and Multiple MyelomaRekha Chandran0Miklos Simon1Stephen E. Spurgeon2Department of Hematology and Oncology, Medical College Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USACompass Oncology, 5050 NE Hoyt Street, Suite 256, Portland, OR 97213, USAKnight Cancer Institute, Oregon Health Sciences and University, 3181 SW Sam Jackson Park Road, Portland, OR, USAThe simultaneous presentation of the Hodgkin lymphoma and multiple myeloma in the absence of prior chemotherapy or radiation is very rare. Here, we discuss a 72-year-old patient who initially presented with generalized pruritis. Workup led to a diagnosis of multiple myeloma which progressed and required treatment. As part of his pretreatment workup, an MRI was performed to evaluate skeletal lesions. This revealed diffuse and bulky adenopathy which was confirmed by PET. A biopsy of an axillary node was consistent with the nodular sclerosing type Hodgkin lymphoma. He was treated with adriamycin, bleomycin, vinblastine, and dacarbazine (ABVD) chemotherapy × 6 resulting in complete resolution of his adenopathy and pruritis as well as improvement in his myeloma.http://dx.doi.org/10.1155/2013/398769
spellingShingle Rekha Chandran
Miklos Simon
Stephen E. Spurgeon
Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma
Case Reports in Hematology
title Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma
title_full Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma
title_fullStr Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma
title_full_unstemmed Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma
title_short Concurrent Presentation of Hodgkin Lymphoma and Multiple Myeloma
title_sort concurrent presentation of hodgkin lymphoma and multiple myeloma
url http://dx.doi.org/10.1155/2013/398769
work_keys_str_mv AT rekhachandran concurrentpresentationofhodgkinlymphomaandmultiplemyeloma
AT miklossimon concurrentpresentationofhodgkinlymphomaandmultiplemyeloma
AT stephenespurgeon concurrentpresentationofhodgkinlymphomaandmultiplemyeloma