Swift and Complete Healing of Digital Ulcers after Macitentan Treatment

Digital ulcers are a burdensome and painful condition with sparse options of treatment. We report the case of a 78-year-old female patient with limited cutaneous systemic sclerosis that sequentially developed digital ulcers. After the appearance of digital ulcers in the soles of her feet she was suc...

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Main Author: Emilio Giner Serret
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2016/1718309
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author Emilio Giner Serret
author_facet Emilio Giner Serret
author_sort Emilio Giner Serret
collection DOAJ
description Digital ulcers are a burdensome and painful condition with sparse options of treatment. We report the case of a 78-year-old female patient with limited cutaneous systemic sclerosis that sequentially developed digital ulcers. After the appearance of digital ulcers in the soles of her feet she was successfully treated with bosentan. The report of two new digital ulcers in her hands 9 months later alongside with elevated transaminase levels led to a switch to macitentan treatment. A swift and complete healing of both digital ulcers was observed after 3 months, with the restoration of normal biochemical values.
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spelling doaj-art-fc8e5fb853ad4e7ca153833b25837fc72025-02-03T01:01:58ZengWileyCase Reports in Rheumatology2090-68892090-68972016-01-01201610.1155/2016/17183091718309Swift and Complete Healing of Digital Ulcers after Macitentan TreatmentEmilio Giner Serret0Servicio de Reumatología, Hospital Obispo Polanco, Teruel, SpainDigital ulcers are a burdensome and painful condition with sparse options of treatment. We report the case of a 78-year-old female patient with limited cutaneous systemic sclerosis that sequentially developed digital ulcers. After the appearance of digital ulcers in the soles of her feet she was successfully treated with bosentan. The report of two new digital ulcers in her hands 9 months later alongside with elevated transaminase levels led to a switch to macitentan treatment. A swift and complete healing of both digital ulcers was observed after 3 months, with the restoration of normal biochemical values.http://dx.doi.org/10.1155/2016/1718309
spellingShingle Emilio Giner Serret
Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
Case Reports in Rheumatology
title Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_full Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_fullStr Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_full_unstemmed Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_short Swift and Complete Healing of Digital Ulcers after Macitentan Treatment
title_sort swift and complete healing of digital ulcers after macitentan treatment
url http://dx.doi.org/10.1155/2016/1718309
work_keys_str_mv AT emilioginerserret swiftandcompletehealingofdigitalulcersaftermacitentantreatment