Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology

Exploring the Therapeutic Landscape: A Narrative Review on Topical and Oral Phosphodiesterase-4 Inhibitors in Dermatology

Phosphodiesterase-4 (PDE4) is involved in the synthesis of inflammatory cytokines that mediate several chronic inflammatory disorders, including psoriasis and atopic dermatitis. In recent years, the therapeutic armamentarium in dermatology has expanded with the introduction of PDE4 inhibitors, both...

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Bibliographic Details
Main Authors: Elena Carmona-Rocha, Lluís Rusiñol, Lluís Puig
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Pharmaceutics
Subjects:
phosphodiesterase-4
PDE4
apremilast
roflumilast
orismilast
mufemilast
Online Access:https://www.mdpi.com/1999-4923/17/1/91
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