The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity

Drug use and abuse continue to be a large public health concern worldwide. Over the past decade, novel or atypical drugs have emerged and become increasingly popular. In the recent past, compounds similar to tetrahydrocannabinoid (THC), the active ingredient of marijuana, have been synthetically pro...

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Main Authors: Jose Orsini, Christa Blaak, Eric Tam, Salil Rajayer, Joaquin Morante, Angela Yeh, Ashvin Butala
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2015/542490
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author Jose Orsini
Christa Blaak
Eric Tam
Salil Rajayer
Joaquin Morante
Angela Yeh
Ashvin Butala
author_facet Jose Orsini
Christa Blaak
Eric Tam
Salil Rajayer
Joaquin Morante
Angela Yeh
Ashvin Butala
author_sort Jose Orsini
collection DOAJ
description Drug use and abuse continue to be a large public health concern worldwide. Over the past decade, novel or atypical drugs have emerged and become increasingly popular. In the recent past, compounds similar to tetrahydrocannabinoid (THC), the active ingredient of marijuana, have been synthetically produced and offered commercially as legal substances. Since the initial communications of their abuse in 2008, few case reports have been published illustrating the misuse of these substances with signs and symptoms of intoxication. Even though synthetic cannabinoids have been restricted, they are still readily available across USA and their use has been dramatically increasing, with a concomitant increment in reports to poison control centers and emergency department (ED) visits. We describe a case of acute hypoxemic/hypercapnic respiratory failure as a consequence of acute congestive heart failure (CHF) developed from myocardial stunning resulting from a non-ST-segment elevation myocardial infarction (MI) following the consumption of synthetic cannabinoids.
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publishDate 2015-01-01
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series Case Reports in Critical Care
spelling doaj-art-fc61ecc49b9f40b68313ccb736684f842025-02-03T01:30:13ZengWileyCase Reports in Critical Care2090-64202090-64392015-01-01201510.1155/2015/542490542490The Wide and Unpredictable Scope of Synthetic Cannabinoids ToxicityJose Orsini0Christa Blaak1Eric Tam2Salil Rajayer3Joaquin Morante4Angela Yeh5Ashvin Butala6Department of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADepartment of Medicine, New York University School of Medicine, Woodhull Medical and Mental Health Center, 760 Broadway, Brooklyn, NY 11206, USADrug use and abuse continue to be a large public health concern worldwide. Over the past decade, novel or atypical drugs have emerged and become increasingly popular. In the recent past, compounds similar to tetrahydrocannabinoid (THC), the active ingredient of marijuana, have been synthetically produced and offered commercially as legal substances. Since the initial communications of their abuse in 2008, few case reports have been published illustrating the misuse of these substances with signs and symptoms of intoxication. Even though synthetic cannabinoids have been restricted, they are still readily available across USA and their use has been dramatically increasing, with a concomitant increment in reports to poison control centers and emergency department (ED) visits. We describe a case of acute hypoxemic/hypercapnic respiratory failure as a consequence of acute congestive heart failure (CHF) developed from myocardial stunning resulting from a non-ST-segment elevation myocardial infarction (MI) following the consumption of synthetic cannabinoids.http://dx.doi.org/10.1155/2015/542490
spellingShingle Jose Orsini
Christa Blaak
Eric Tam
Salil Rajayer
Joaquin Morante
Angela Yeh
Ashvin Butala
The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity
Case Reports in Critical Care
title The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity
title_full The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity
title_fullStr The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity
title_full_unstemmed The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity
title_short The Wide and Unpredictable Scope of Synthetic Cannabinoids Toxicity
title_sort wide and unpredictable scope of synthetic cannabinoids toxicity
url http://dx.doi.org/10.1155/2015/542490
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