Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals
SARS-C0V-2 has quickly caused a pandemic. The distribution of vaccines is presently underway in an effort to stop the viral transmission and stop fatalities, several vaccinations have been created to decrease COVID virus disease, in 2019, the development of vaccine-induced population immunity is an...
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middle technical university
2023-06-01
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| Series: | Journal of Techniques |
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| Online Access: | https://journal.mtu.edu.iq/index.php/MTU/article/view/1267 |
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| author | Najat Saeed Hussein Izzat Abdulsatar Al-Rayahi Salwa S. Muhsin Redhwan Abdul Kareem Alameer |
| author_facet | Najat Saeed Hussein Izzat Abdulsatar Al-Rayahi Salwa S. Muhsin Redhwan Abdul Kareem Alameer |
| author_sort | Najat Saeed Hussein |
| collection | DOAJ |
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SARS-C0V-2 has quickly caused a pandemic. The distribution of vaccines is presently underway in an effort to stop the viral transmission and stop fatalities, several vaccinations have been created to decrease COVID virus disease, in 2019, the development of vaccine-induced population immunity is an important global strategy. Review of the anti-spike protein receptor-binding domain (S-RBD) a person's level of immune response to antibody strategy can be used to assess SARS-CoV-2 viral infection in 2019. Their efficacy, safety, and immunogenicity in various population are not thoroughly understood. The objective of this study was to evaluate the vaccinations adverse effects as well as determine the immunogenicity of the messenger ribonucleic acid (mRNA) BNT162b2 vaccines through the production of IgG and neutralizing antibodies against the protein s subunit. A total of 41 vaccinated individuals with Pfizer-BioNTech COVID-19 vaccine, as well as (10) non vaccinated were included in the study. Measurements of Neutralizing antibody (Nab) levels and CoV-IgG levels were tested by fluorescence Immunochromatographic assay. IgG and Nab levels showed a significant difference between its level in the sera of vaccinated and controls (p<0.05). This means the majority of immunization recipients between the ages of 18 -50 years can develop an immunological response to the SARS-Cov-2 vaccine.
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| format | Article |
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| institution | Kabale University |
| issn | 1818-653X 2708-8383 |
| language | English |
| publishDate | 2023-06-01 |
| publisher | middle technical university |
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| series | Journal of Techniques |
| spelling | doaj-art-fc3779210dab4900b3f68ac9588167bd2025-01-19T11:01:50Zengmiddle technical universityJournal of Techniques1818-653X2708-83832023-06-015210.51173/jt.v5i2.1267Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi IndividualsNajat Saeed Hussein0Izzat Abdulsatar Al-Rayahi1Salwa S. Muhsin2Redhwan Abdul Kareem Alameer3College of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqCollege of Health & Medical Technology - Baghdad, Middle Technical University, Baghdad, IraqInstitute of Medical Technology / Baghdad, Middle Technical University, Baghdad, IraqCollege of Medicine and Health Sciences, IBB university, Yemen SARS-C0V-2 has quickly caused a pandemic. The distribution of vaccines is presently underway in an effort to stop the viral transmission and stop fatalities, several vaccinations have been created to decrease COVID virus disease, in 2019, the development of vaccine-induced population immunity is an important global strategy. Review of the anti-spike protein receptor-binding domain (S-RBD) a person's level of immune response to antibody strategy can be used to assess SARS-CoV-2 viral infection in 2019. Their efficacy, safety, and immunogenicity in various population are not thoroughly understood. The objective of this study was to evaluate the vaccinations adverse effects as well as determine the immunogenicity of the messenger ribonucleic acid (mRNA) BNT162b2 vaccines through the production of IgG and neutralizing antibodies against the protein s subunit. A total of 41 vaccinated individuals with Pfizer-BioNTech COVID-19 vaccine, as well as (10) non vaccinated were included in the study. Measurements of Neutralizing antibody (Nab) levels and CoV-IgG levels were tested by fluorescence Immunochromatographic assay. IgG and Nab levels showed a significant difference between its level in the sera of vaccinated and controls (p<0.05). This means the majority of immunization recipients between the ages of 18 -50 years can develop an immunological response to the SARS-Cov-2 vaccine. https://journal.mtu.edu.iq/index.php/MTU/article/view/1267SARS-CoV2COVID-19IgG LevelNeutralizing AntibodyVaccination |
| spellingShingle | Najat Saeed Hussein Izzat Abdulsatar Al-Rayahi Salwa S. Muhsin Redhwan Abdul Kareem Alameer Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals Journal of Techniques SARS-CoV2 COVID-19 IgG Level Neutralizing Antibody Vaccination |
| title | Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals |
| title_full | Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals |
| title_fullStr | Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals |
| title_full_unstemmed | Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals |
| title_short | Comparison of IgG and Neutralizing Antibody Response After Pfizer BioNTech COVID-19 Vaccine Among Iraqi Individuals |
| title_sort | comparison of igg and neutralizing antibody response after pfizer biontech covid 19 vaccine among iraqi individuals |
| topic | SARS-CoV2 COVID-19 IgG Level Neutralizing Antibody Vaccination |
| url | https://journal.mtu.edu.iq/index.php/MTU/article/view/1267 |
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