Mitochondrial-ER Contact Sites and Tethers Influence the Biosynthesis and Function of Coenzyme Q

Mitochondrial-ER Contact Sites and Tethers Influence the Biosynthesis and Function of Coenzyme Q

Coenzyme Q (CoQ) is an essential redox-active lipid that plays a major role in the electron transport chain, driving mitochondrial ATP synthesis. In Saccharomyces cerevisiae (yeast), CoQ biosynthesis occurs exclusively in the mitochondrial matrix via a large protein-lipid complex, the CoQ synthome,...

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Bibliographic Details
Main Authors: Noelle Alexa Novales, Hadar Meyer, Yeynit Asraf, Maya Schuldiner, Catherine F. Clarke
Format: Article
Language:English
Published: SAGE Publishing 2025-02-01
Series:Contact
Online Access:https://doi.org/10.1177/25152564251316350
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