Assessing concordance between RNA-Seq and NanoString technologies in Ebola-infected nonhuman primates using machine learning

Assessing concordance between RNA-Seq and NanoString technologies in Ebola-infected nonhuman primates using machine learning

Abstract This study evaluates the concordance between RNA sequencing (RNA-Seq) and NanoString technologies for gene expression analysis in non-human primates (NHPs) infected with Ebola virus (EBOV). A detailed comparison of both platforms revealed a strong correlation, with Spearman coefficients for...

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Bibliographic Details
Main Authors: Mostafa Rezapour, Aarthi Narayanan, Wyatt H. Mowery, Metin Nafi Gurcan
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Genomics
Subjects:
RNA sequencing
NanoString technology
Machine learning
Gene expression analysis
Concordance analysis
Online Access:https://doi.org/10.1186/s12864-025-11553-6
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