Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review
Uterine mesenchymal tumors other than leiomyosarcoma, carcinosarcoma, and endometrial stromal sarcomas are extremely uncommon. We describe a case of epithelioid angiosarcoma of the uterus and review previous literature on such rare tumors. A 48-year-old woman presented with a 1-year history of abdom...
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| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Obstetrics and Gynecology |
| Online Access: | http://dx.doi.org/10.1155/2018/7591769 |
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| _version_ | 1832562781865377792 |
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| author | Takeya Hara Ai Miyoshi Yuji Kamei Nao Wakui Akiko Fujishiro Serika Kanao Hirokazu Naoi Hirofumi Otsuka Takeshi Yokoi |
| author_facet | Takeya Hara Ai Miyoshi Yuji Kamei Nao Wakui Akiko Fujishiro Serika Kanao Hirokazu Naoi Hirofumi Otsuka Takeshi Yokoi |
| author_sort | Takeya Hara |
| collection | DOAJ |
| description | Uterine mesenchymal tumors other than leiomyosarcoma, carcinosarcoma, and endometrial stromal sarcomas are extremely uncommon. We describe a case of epithelioid angiosarcoma of the uterus and review previous literature on such rare tumors. A 48-year-old woman presented with a 1-year history of abdominal fullness and 10kg weight loss. Pelvic magnetic resonance imaging (MRI) revealed a huge (30×18cm) uterus accompanied by degeneration and necrosis. She underwent supracervical hysterectomy and right salpingo-oophorectomy. We postoperatively diagnosed the mass as an epithelioid angiosarcoma arising from a leiomyoma. Vasodilatation was observed within the range of 2 cm × several mm in the leiomyoma, and proliferation of atypical cells was observed covering the surface of the luminal side. The tumor showed a partly fine vascular structure and was associated with obvious nuclear atypia and mitotic figures. She received 6 courses of adjuvant chemotherapy with paclitaxel, epirubicin, and carboplatin, and there have been no signs of recurrence for 10 months. |
| format | Article |
| id | doaj-art-fc0c3140218440ddb4cd9a55d57273b1 |
| institution | Kabale University |
| issn | 2090-6684 2090-6692 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Obstetrics and Gynecology |
| spelling | doaj-art-fc0c3140218440ddb4cd9a55d57273b12025-02-03T01:21:57ZengWileyCase Reports in Obstetrics and Gynecology2090-66842090-66922018-01-01201810.1155/2018/75917697591769Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature ReviewTakeya Hara0Ai Miyoshi1Yuji Kamei2Nao Wakui3Akiko Fujishiro4Serika Kanao5Hirokazu Naoi6Hirofumi Otsuka7Takeshi Yokoi8Department of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanDepartment of Obstetrics and Gynecology, Kaizuka City Hospital, Osaka, JapanUterine mesenchymal tumors other than leiomyosarcoma, carcinosarcoma, and endometrial stromal sarcomas are extremely uncommon. We describe a case of epithelioid angiosarcoma of the uterus and review previous literature on such rare tumors. A 48-year-old woman presented with a 1-year history of abdominal fullness and 10kg weight loss. Pelvic magnetic resonance imaging (MRI) revealed a huge (30×18cm) uterus accompanied by degeneration and necrosis. She underwent supracervical hysterectomy and right salpingo-oophorectomy. We postoperatively diagnosed the mass as an epithelioid angiosarcoma arising from a leiomyoma. Vasodilatation was observed within the range of 2 cm × several mm in the leiomyoma, and proliferation of atypical cells was observed covering the surface of the luminal side. The tumor showed a partly fine vascular structure and was associated with obvious nuclear atypia and mitotic figures. She received 6 courses of adjuvant chemotherapy with paclitaxel, epirubicin, and carboplatin, and there have been no signs of recurrence for 10 months.http://dx.doi.org/10.1155/2018/7591769 |
| spellingShingle | Takeya Hara Ai Miyoshi Yuji Kamei Nao Wakui Akiko Fujishiro Serika Kanao Hirokazu Naoi Hirofumi Otsuka Takeshi Yokoi Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review Case Reports in Obstetrics and Gynecology |
| title | Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review |
| title_full | Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review |
| title_fullStr | Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review |
| title_full_unstemmed | Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review |
| title_short | Epithelioid Angiosarcoma Arising from a Huge Leiomyoma: A Case Report and a Literature Review |
| title_sort | epithelioid angiosarcoma arising from a huge leiomyoma a case report and a literature review |
| url | http://dx.doi.org/10.1155/2018/7591769 |
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