LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness

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Main Authors: Serkan Levent, Abeer Elriş, Hazal Avcı, Ülfet Erdoğan Uzunoğlu, Saniye Özcan, Nafiz Öncü Can
Format: Article
Language:English
Published: American Chemical Society 2025-04-01
Series:ACS Omega
Online Access:https://doi.org/10.1021/acsomega.5c00569
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author Serkan Levent
Abeer Elriş
Hazal Avcı
Ülfet Erdoğan Uzunoğlu
Saniye Özcan
Nafiz Öncü Can
author_facet Serkan Levent
Abeer Elriş
Hazal Avcı
Ülfet Erdoğan Uzunoğlu
Saniye Özcan
Nafiz Öncü Can
author_sort Serkan Levent
collection DOAJ
format Article
id doaj-art-fbe87b9f9b0e44ca8011a74e6e6b220c
institution DOAJ
issn 2470-1343
language English
publishDate 2025-04-01
publisher American Chemical Society
record_format Article
series ACS Omega
spelling doaj-art-fbe87b9f9b0e44ca8011a74e6e6b220c2025-08-20T03:11:30ZengAmerican Chemical SocietyACS Omega2470-13432025-04-011017178361784610.1021/acsomega.5c00569LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its WhitenessSerkan Levent0Abeer Elriş1Hazal Avcı2Ülfet Erdoğan Uzunoğlu3Saniye Özcan4Nafiz Öncü Can5Department of Analytical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, TurkeyDepartment of Analytical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, TurkeyDepartment of Analytical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, TurkeyDepartment of Chemistry and Biochemistry, Clarkson University, Potsdam, New York, United StatesDepartment of Analytical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, TurkeyDepartment of Analytical Chemistry, Faculty of Pharmacy, Anadolu University, Eskisehir, Turkeyhttps://doi.org/10.1021/acsomega.5c00569
spellingShingle Serkan Levent
Abeer Elriş
Hazal Avcı
Ülfet Erdoğan Uzunoğlu
Saniye Özcan
Nafiz Öncü Can
LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness
ACS Omega
title LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness
title_full LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness
title_fullStr LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness
title_full_unstemmed LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness
title_short LC-MS/MS and LC-PDA Methods for Robust Determination of Glycerol Phenylbutyrate in Biological Fluids and High-Resolution Mass Spectrometric Identification of Forced Degradation Product and Its Whiteness
title_sort lc ms ms and lc pda methods for robust determination of glycerol phenylbutyrate in biological fluids and high resolution mass spectrometric identification of forced degradation product and its whiteness
url https://doi.org/10.1021/acsomega.5c00569
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