Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential

Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential

Unsweetened natural cocoa (UNCP) was evaluated for reproductive toxicity in rats. A preliminary genotoxic potential was evaluated by the DNA comet assay test using C57Bl/6 mice. Both therapeutic dose (TD; 900 mg/kg) and high dose (HD; 9000 mg/kg) of UNCP were used. White Wistar rats were used in two...

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Main Authors: I. J. Asiedu-Gyekye, T. G. Borovskaya, M. E. Poluektova, А. V. Vychuzhanina, Y. А. Shchemerovа, S. I. Kamalova, V. A. Grgoreva, P. Amoateng, K. E. Kukuia, A. A. Kwapong, L. Allotey Babington, S. K. Amponsah, B. B. N’guessan
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2021/6114672
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