The Effects of Affinity Mediated Clonal Expansion of Premigrant Thymocytes on the Periphery T-Cell Repertoire

The immune system maintains a highly diverse T-cell repertoire,which is shaped by active interactions between developing thymocytesand endogenous peptide/MHC molecules through the principle ofpositive and negative selections. Detours et al. developed aquantitative model addressing key immunologic no...

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Bibliographic Details
Main Author: Guanyu Wang
Format: Article
Language:English
Published: AIMS Press 2004-10-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2005.2.153
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