Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia

Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized blood vessels. The disease has a prevalence in studies ranging from 3 to 15.7 cases per 100,000, with a noted increasing incidence and prevalence in mo...

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Main Authors: Ramy Magdy Hanna, Eduardo Lopez, James Wilson
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2017/6501738
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author Ramy Magdy Hanna
Eduardo Lopez
James Wilson
author_facet Ramy Magdy Hanna
Eduardo Lopez
James Wilson
author_sort Ramy Magdy Hanna
collection DOAJ
description Granulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized blood vessels. The disease has a prevalence in studies ranging from 3 to 15.7 cases per 100,000, with a noted increasing incidence and prevalence in more recent studies. Pulmonary manifestations include hemorrhage, lung cavitary lesions, and pulmonary fibrosis. Within the kidney, GPA is known to cause rapidly progressive pauci-immune crescentic glomerulonephritis. Rare and severe cardiovascular manifestations include pericarditis, arrhythmias, myocarditis, and aortic valve disease. Our patient is a 43-year-old female with typical pulmonary and renal lesions from GPA and also acute myocarditis, multiple episodes of ventricular tachycardia, and a severe reactive thrombocytosis.
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spelling doaj-art-fb6c377babb24361a96d7305143043df2025-02-03T01:20:22ZengWileyCase Reports in Medicine1687-96271687-96352017-01-01201710.1155/2017/65017386501738Granulomatosis with Polyangiitis with Myocarditis and Ventricular TachycardiaRamy Magdy Hanna0Eduardo Lopez1James Wilson2Division of Nephrology, Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, USADivision of Nephrology, Department of Medicine, Kaiser Permanente Medical Center, Panorama City, Los Angeles, CA, USASurgical Consultative Nephrology, UCLA Stone Center, Los Angeles, CA, USAGranulomatosis with polyangiitis (GPA), previously known as Wegener’s granulomatosis, is a pulmonary-renal syndrome affecting small and medium sized blood vessels. The disease has a prevalence in studies ranging from 3 to 15.7 cases per 100,000, with a noted increasing incidence and prevalence in more recent studies. Pulmonary manifestations include hemorrhage, lung cavitary lesions, and pulmonary fibrosis. Within the kidney, GPA is known to cause rapidly progressive pauci-immune crescentic glomerulonephritis. Rare and severe cardiovascular manifestations include pericarditis, arrhythmias, myocarditis, and aortic valve disease. Our patient is a 43-year-old female with typical pulmonary and renal lesions from GPA and also acute myocarditis, multiple episodes of ventricular tachycardia, and a severe reactive thrombocytosis.http://dx.doi.org/10.1155/2017/6501738
spellingShingle Ramy Magdy Hanna
Eduardo Lopez
James Wilson
Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
Case Reports in Medicine
title Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
title_full Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
title_fullStr Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
title_full_unstemmed Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
title_short Granulomatosis with Polyangiitis with Myocarditis and Ventricular Tachycardia
title_sort granulomatosis with polyangiitis with myocarditis and ventricular tachycardia
url http://dx.doi.org/10.1155/2017/6501738
work_keys_str_mv AT ramymagdyhanna granulomatosiswithpolyangiitiswithmyocarditisandventriculartachycardia
AT eduardolopez granulomatosiswithpolyangiitiswithmyocarditisandventriculartachycardia
AT jameswilson granulomatosiswithpolyangiitiswithmyocarditisandventriculartachycardia