Oxygenation and function of endocrine bioartificial pancreatic tissue constructs under flow for preclinical optimization

Islet transplantation and more recently stem cell-derived islets were shown to successfully re-establish glycemic control in people with type 1 diabetes under immunosuppression. These results were achieved through intraportal infusion which leads to early graft losses and limits the capacity to cont...

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Bibliographic Details
Main Authors: Brenden N Moeun, Florent Lemaire, Alexandra M Smink, Hamid Ebrahimi Orimi, Richard L Leask, Paul de Vos, Corinne A Hoesli
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:Journal of Tissue Engineering
Online Access:https://doi.org/10.1177/20417314241284826
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