Atypical hemolytic uremic syndrome with a C3 variant following COVID-19: a case report

Atypical hemolytic uremic syndrome with a C3 variant following COVID-19: a case report

Atypical hemolytic uremic syndrome (aHUS) is a form of thrombotic microangiopathy (TMA) characterized by the triad of microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury, and is caused by overactivation of the alternative complement pathway. A 13-year-old Japanese boy with a...

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Bibliographic Details
Main Authors: Masato Ando, Kazuo Kubota, Saori Kadowaki, Minako Kawamoto, Norio Kawamoto, Haruka Okamoto, Soichiro Nagaya, Yuki Miwa, Hidenori Ohnishi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Pediatrics
Subjects:
atypical hemolytic uremic syndrome
GOF C3 variant
severe acute respiratory syndrome coronavirus 2
alternative complement pathway
inborn errors of immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1507727/full
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https://www.frontiersin.org/articles/10.3389/fped.2025.1507727/full

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