SECTM1 acts as an immune-related biomarker of poor prognosis and promotes cancer progression by modulating M2 macrophage polarization in esophageal squamous cell carcinoma

SECTM1 acts as an immune-related biomarker of poor prognosis and promotes cancer progression by modulating M2 macrophage polarization in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is the most prevalent primary malignant esophageal tumor in China and has a poor prognosis, but lacks effective diagnostic and prognostic biomarkers. Through single-sample gene set enrichment analysis (ssGSEA), we conducted immune genomic analysis based on 2...

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Bibliographic Details
Main Authors: Pengzhou Kong, Ye Jiao, Meng Sun, Zhinan Zhou, Yingying Zhang, Xin Yang, Jing Ren, Mengyuan Yang, Yanyan Dong, Bin Song
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
ESCC
SECTM1
immune
biomarker
macrophage
CCL5
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1507227/full
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