Impact of body composition on pathological response to neoadjuvant immunotherapy in dMMR/MSI-H colorectal cancer

BackgroundObesity and overweight have been suggested as a potential predictor of favorable outcomes in certain malignancies treated with immunotherapy. However, most studies have relied on BMI as a proxy for adiposity, without fully considering the distinct roles of fat and lean tissues. This study...

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Main Authors: Ziyang Zeng, Jian Zhou, Weili Zhang, Jianhong Peng, Yuan Li, E-er-man-bie-ke Jin-si-han, Hao Wang, Shaopu Lian, Cheng Feng, Chuanmiao Xie, Zhizhong Pan, Zhenhai Lu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1589869/full
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