Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor
This paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | International Journal of Electrochemistry |
| Online Access: | http://dx.doi.org/10.4061/2011/171389 |
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| author | Mariana Calora Quintino de Oliveira Marcos Roberto de Vasconcelos Lanza José Luis Paz Jara Maria Del Pilar Taboada Sotomayor |
| author_facet | Mariana Calora Quintino de Oliveira Marcos Roberto de Vasconcelos Lanza José Luis Paz Jara Maria Del Pilar Taboada Sotomayor |
| author_sort | Mariana Calora Quintino de Oliveira |
| collection | DOAJ |
| description | This paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with a DSA anode. The process efficiency was monitored at real time by the biomimetic sensor constructed by modifying a glassy carbon electrode with a Nafion membrane doped with iron tetrapyridinoporphyrazine (FeTPyPz). Simultaneously, we carried out off-line analysis by liquid chromatography (HPLC) during the experiments in order to validate the proposed system. In addition, to investigate the degradation products of the paracetamol electrolysis, we used the techniques of UPLC/MS and GC/MS. |
| format | Article |
| id | doaj-art-fb1a14afe0f7408bab0432fc01d207ac |
| institution | Kabale University |
| issn | 2090-3537 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Electrochemistry |
| spelling | doaj-art-fb1a14afe0f7408bab0432fc01d207ac2025-02-03T01:08:49ZengWileyInternational Journal of Electrochemistry2090-35372011-01-01201110.4061/2011/171389171389Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic SensorMariana Calora Quintino de Oliveira0Marcos Roberto de Vasconcelos Lanza1José Luis Paz Jara2Maria Del Pilar Taboada Sotomayor3Departamento de Química Analítica, IQ, Universidade Estadual Paulista, 14801-970 Araraquara, SP, BrazilDepartamento de Química e Física Molecular, IQSC, Universidade de São Paulo, 13560-970 São Carlos, SP, BrazilInstituto de Química, Universidade Estadual de Campinas, 13083-970 Campinas, SP, BrazilDepartamento de Química Analítica, IQ, Universidade Estadual Paulista, 14801-970 Araraquara, SP, BrazilThis paper reports, for the first time, the online monitoring to the electrochemical degradation of the paracetamol using a biomimetic sensor coupled to a Flow Injection Analysis (FIA) system. The electrochemical degradation of the drug was carried out in aqueous medium using a flow-by reactor with a DSA anode. The process efficiency was monitored at real time by the biomimetic sensor constructed by modifying a glassy carbon electrode with a Nafion membrane doped with iron tetrapyridinoporphyrazine (FeTPyPz). Simultaneously, we carried out off-line analysis by liquid chromatography (HPLC) during the experiments in order to validate the proposed system. In addition, to investigate the degradation products of the paracetamol electrolysis, we used the techniques of UPLC/MS and GC/MS.http://dx.doi.org/10.4061/2011/171389 |
| spellingShingle | Mariana Calora Quintino de Oliveira Marcos Roberto de Vasconcelos Lanza José Luis Paz Jara Maria Del Pilar Taboada Sotomayor Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor International Journal of Electrochemistry |
| title | Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor |
| title_full | Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor |
| title_fullStr | Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor |
| title_full_unstemmed | Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor |
| title_short | Online Monitoring of Electrochemical Degradation of Paracetamol through a Biomimetic Sensor |
| title_sort | online monitoring of electrochemical degradation of paracetamol through a biomimetic sensor |
| url | http://dx.doi.org/10.4061/2011/171389 |
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