Experiences and overall impact reported by people living with obesity: results from a multinational study

Objectives: To explore the impact of obesity on clinical outcomes, health-related quality of life, emotional well-being, and work productivity in people/patients with obesity across six countries by body mass index and the presence of complications. Methods: Adelphi Real World Obesity Disease Specif...

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Main Authors: Esther Artime, Swarna Khare, Sarah Zimner-Rapuch, Josefine Redig, Caragh Flannery, Victoria Higgins, Andrea Leith, Ashley Mortimer, Bruno Halpern, Nasreen Alfaris
Format: Article
Language:English
Published: SAGE Publishing 2025-01-01
Series:SAGE Open Medicine
Online Access:https://doi.org/10.1177/20503121241313082
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author Esther Artime
Swarna Khare
Sarah Zimner-Rapuch
Josefine Redig
Caragh Flannery
Victoria Higgins
Andrea Leith
Ashley Mortimer
Bruno Halpern
Nasreen Alfaris
author_facet Esther Artime
Swarna Khare
Sarah Zimner-Rapuch
Josefine Redig
Caragh Flannery
Victoria Higgins
Andrea Leith
Ashley Mortimer
Bruno Halpern
Nasreen Alfaris
author_sort Esther Artime
collection DOAJ
description Objectives: To explore the impact of obesity on clinical outcomes, health-related quality of life, emotional well-being, and work productivity in people/patients with obesity across six countries by body mass index and the presence of complications. Methods: Adelphi Real World Obesity Disease Specific Programme™ captured data related to physicians and their consulting people/patients with obesity on a weight management program or anti-obesity medication in Brazil, Canada, China, Japan, Kingdom of Saudi Arabia, and the United Arab Emirates from April to December 2022. Physicians reported data for up to eight qualifying people/patients with obesity. People/patients with obesity voluntarily completed outcome measures: 36-Item Short Form Health Survey, emotional well-being, and Work Productivity and Activity Impairment. Results: Of 1506 people/patients with obesity, 58% were female (mean ± standard deviation age: 41 ± 12.7 years; body mass index: 32.3 kg/m 2  ± 7.7 kg/m 2 ). Overall, 82% had ⩾1 complication (median and interquartile range: 2.0 (1.0–3.0)). People/patients with obesity struggled with weight for a mean ± SD of 64.1 ± 86.6 months with a median (interquartile range) of 3.0 (2.0–5.0) weight-loss attempts. Mean ± standard deviation 36-Item Short Form Health Survey scores for people/patients with obesity above the obesity threshold showed impairment in general health (42.3 ± 11.5), social functioning (44.3 ± 9.2), role-emotional (46.0 ± 9.3), and mental health (45.7 ± 9.6). People/patients with obesity with complications showed similar impairment. People/patients with obesity reported bother/embarrassment about their weight, with 72% worried about future weight gain. Work productivity and activity impairment scores among people/patients with obesity above the obesity threshold showed impairment in activity (36%), overall work (34%), and presenteeism (31%). Findings were similar for people/patients with obesity with complications. Conclusion: Results suggest that obesity alongside the presence of complications negatively impacts health-related quality of life, emotional well-being, and work productivity, reinforcing the need for comprehensive interventions for this complex health issue.
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spelling doaj-art-fb01285ea6cd4298bd2344207c4751dc2025-01-27T15:04:22ZengSAGE PublishingSAGE Open Medicine2050-31212025-01-011310.1177/20503121241313082Experiences and overall impact reported by people living with obesity: results from a multinational studyEsther Artime0Swarna Khare1Sarah Zimner-Rapuch2Josefine Redig3Caragh Flannery4Victoria Higgins5Andrea Leith6Ashley Mortimer7Bruno Halpern8Nasreen Alfaris9Eli Lilly and Company, Alcobendas, SpainEli Lilly and Company, Bracknell, UKEli Lilly and Company, Neuilly-sur-Seine, FranceEli Lilly and Company, Stockholm, SwedenEli Lilly and Company, Cork, IrelandAdelphi Real World, Bollington, UKAdelphi Real World, Bollington, UKAdelphi Real World, Bollington, UKDepartment of Obesity, Hospital 9 de Julho, São Paulo, BrazilEndocrinology Diabetes, Metabolism, and Obesity Medicine, Obesity, Endocrine, and Metabolism Center (OEMC), King Fahad Medical City (KFMC), Riyadh, Saudi ArabiaObjectives: To explore the impact of obesity on clinical outcomes, health-related quality of life, emotional well-being, and work productivity in people/patients with obesity across six countries by body mass index and the presence of complications. Methods: Adelphi Real World Obesity Disease Specific Programme™ captured data related to physicians and their consulting people/patients with obesity on a weight management program or anti-obesity medication in Brazil, Canada, China, Japan, Kingdom of Saudi Arabia, and the United Arab Emirates from April to December 2022. Physicians reported data for up to eight qualifying people/patients with obesity. People/patients with obesity voluntarily completed outcome measures: 36-Item Short Form Health Survey, emotional well-being, and Work Productivity and Activity Impairment. Results: Of 1506 people/patients with obesity, 58% were female (mean ± standard deviation age: 41 ± 12.7 years; body mass index: 32.3 kg/m 2  ± 7.7 kg/m 2 ). Overall, 82% had ⩾1 complication (median and interquartile range: 2.0 (1.0–3.0)). People/patients with obesity struggled with weight for a mean ± SD of 64.1 ± 86.6 months with a median (interquartile range) of 3.0 (2.0–5.0) weight-loss attempts. Mean ± standard deviation 36-Item Short Form Health Survey scores for people/patients with obesity above the obesity threshold showed impairment in general health (42.3 ± 11.5), social functioning (44.3 ± 9.2), role-emotional (46.0 ± 9.3), and mental health (45.7 ± 9.6). People/patients with obesity with complications showed similar impairment. People/patients with obesity reported bother/embarrassment about their weight, with 72% worried about future weight gain. Work productivity and activity impairment scores among people/patients with obesity above the obesity threshold showed impairment in activity (36%), overall work (34%), and presenteeism (31%). Findings were similar for people/patients with obesity with complications. Conclusion: Results suggest that obesity alongside the presence of complications negatively impacts health-related quality of life, emotional well-being, and work productivity, reinforcing the need for comprehensive interventions for this complex health issue.https://doi.org/10.1177/20503121241313082
spellingShingle Esther Artime
Swarna Khare
Sarah Zimner-Rapuch
Josefine Redig
Caragh Flannery
Victoria Higgins
Andrea Leith
Ashley Mortimer
Bruno Halpern
Nasreen Alfaris
Experiences and overall impact reported by people living with obesity: results from a multinational study
SAGE Open Medicine
title Experiences and overall impact reported by people living with obesity: results from a multinational study
title_full Experiences and overall impact reported by people living with obesity: results from a multinational study
title_fullStr Experiences and overall impact reported by people living with obesity: results from a multinational study
title_full_unstemmed Experiences and overall impact reported by people living with obesity: results from a multinational study
title_short Experiences and overall impact reported by people living with obesity: results from a multinational study
title_sort experiences and overall impact reported by people living with obesity results from a multinational study
url https://doi.org/10.1177/20503121241313082
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