The effect of childhood trauma on bipolar depression

The effect of childhood trauma on bipolar depression

Abstract Childhood trauma (CT) is associated with an earlier onset and a more severe course of bipolar disorder (BD). However, the specific impact of CT on bipolar depression remains unclear. Herein, this study aimed to investigate the effect of CT using depressive episode frequency as a threshold f...

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Bibliographic Details
Main Authors: Hernán F. Guillen-Burgos, Juan F. Gálvez-Flórez, Sergio Moreno-López, María C. Solano, Angela T. H. Kwan, Hernando Santamaria-Garcia, Carlos Gómez-Restrepo, Roger S. McIntyre
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Childhood trauma
Bipolar disorder
Bipolar depression
Mood episodes
Depressive episodes
Trauma
Online Access:https://doi.org/10.1038/s41598-025-98537-4
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