Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis
Objective. To evaluate the risk factors for predicting lymph nodes (LN) posterior to right recurrent laryngeal nerve metastasis in thyroid papillary carcinoma. Methods. PubMed, PMC, EMBASE, and the Cochrane Library were systematically searched for articles published spanning 30/06/2009-30/8/2018 usi...
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| Format: | Article |
| Language: | English |
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Wiley
2019-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2019/7064328 |
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| _version_ | 1832559806180753408 |
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| author | Cunfu Li Jun Xiang Yunjun Wang |
| author_facet | Cunfu Li Jun Xiang Yunjun Wang |
| author_sort | Cunfu Li |
| collection | DOAJ |
| description | Objective. To evaluate the risk factors for predicting lymph nodes (LN) posterior to right recurrent laryngeal nerve metastasis in thyroid papillary carcinoma. Methods. PubMed, PMC, EMBASE, and the Cochrane Library were systematically searched for articles published spanning 30/06/2009-30/8/2018 using multiple search terms. Thirteen articles involving 10,014 patients were reviewed in our meta-analysis. Stata 15.1 software was used for the meta-analysis. Results. The rate of LN posterior to right recurrent laryngeal nerve (LN-prRLN) metastasis was 8.65%. Univariate analysis showed that age (P=0.001), gender (P<0.001), tumour size (P<0.001), lateral LN metastasis (P<0.001), extrathyroidal invasion (P<0.001), multifocality (P=0.005), capsule invasion (P<0.001), tumour location (P=0.076), lymph nodes anterior to right recurrent laryngeal nerve (LN-arRLN) metastasis (P<0.001), and central LN metastasis (P<0.001) were significantly associated with the increased incidence of LN-prRLN metastasis in thyroid papillary carcinoma. Conclusion. PTC patients aged <45, male, and with tumours>1 cm, lateral LN metastasis, extrathyroidal invasion, multifocality, capsule invasion, LN-arRLN metastasis, or central LN metastasis were significantly correlated with lymph nodes posterior to right recurrent laryngeal nerve metastasis, indicating LN-prRLN dissection. |
| format | Article |
| id | doaj-art-fae75f7ebee6468b8200b494592b8480 |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-fae75f7ebee6468b8200b494592b84802025-02-03T01:29:12ZengWileyInternational Journal of Endocrinology1687-83371687-83452019-01-01201910.1155/2019/70643287064328Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-AnalysisCunfu Li0Jun Xiang1Yunjun Wang2Department of Thyroid Surgery, Weihai Central Hospital, Weihai, ChinaDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, ChinaDepartment of Head and Neck Surgery, Fudan University Shanghai Cancer Center, Shanghai, ChinaObjective. To evaluate the risk factors for predicting lymph nodes (LN) posterior to right recurrent laryngeal nerve metastasis in thyroid papillary carcinoma. Methods. PubMed, PMC, EMBASE, and the Cochrane Library were systematically searched for articles published spanning 30/06/2009-30/8/2018 using multiple search terms. Thirteen articles involving 10,014 patients were reviewed in our meta-analysis. Stata 15.1 software was used for the meta-analysis. Results. The rate of LN posterior to right recurrent laryngeal nerve (LN-prRLN) metastasis was 8.65%. Univariate analysis showed that age (P=0.001), gender (P<0.001), tumour size (P<0.001), lateral LN metastasis (P<0.001), extrathyroidal invasion (P<0.001), multifocality (P=0.005), capsule invasion (P<0.001), tumour location (P=0.076), lymph nodes anterior to right recurrent laryngeal nerve (LN-arRLN) metastasis (P<0.001), and central LN metastasis (P<0.001) were significantly associated with the increased incidence of LN-prRLN metastasis in thyroid papillary carcinoma. Conclusion. PTC patients aged <45, male, and with tumours>1 cm, lateral LN metastasis, extrathyroidal invasion, multifocality, capsule invasion, LN-arRLN metastasis, or central LN metastasis were significantly correlated with lymph nodes posterior to right recurrent laryngeal nerve metastasis, indicating LN-prRLN dissection.http://dx.doi.org/10.1155/2019/7064328 |
| spellingShingle | Cunfu Li Jun Xiang Yunjun Wang Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis International Journal of Endocrinology |
| title | Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis |
| title_full | Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis |
| title_fullStr | Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis |
| title_full_unstemmed | Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis |
| title_short | Risk Factors for Predicting Lymph Nodes Posterior to Right Recurrent Laryngeal Nerve (LN-prRLN) Metastasis in Thyroid Papillary Carcinoma: A Meta-Analysis |
| title_sort | risk factors for predicting lymph nodes posterior to right recurrent laryngeal nerve ln prrln metastasis in thyroid papillary carcinoma a meta analysis |
| url | http://dx.doi.org/10.1155/2019/7064328 |
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