Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature
Wegener’s granulomatosis is characterized by a granulomatous arteritis involving the upper and lower respiratory tracts, progressive glomerulonephritis and systemic symptoms attributable to small vessel vasculitis. Although multisystemic manifestations are frequent, involvement of the gastrointestin...
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| Format: | Article |
| Language: | English |
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Wiley
2000-01-01
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| Series: | Canadian Journal of Gastroenterology |
| Online Access: | http://dx.doi.org/10.1155/2000/423569 |
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| _version_ | 1832566450230919168 |
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| author | Glen A Fallows Sean F Hamilton Douglas S Taylor S Bharati Reddy |
| author_facet | Glen A Fallows Sean F Hamilton Douglas S Taylor S Bharati Reddy |
| author_sort | Glen A Fallows |
| collection | DOAJ |
| description | Wegener’s granulomatosis is characterized by a granulomatous arteritis involving the upper and lower respiratory tracts, progressive glomerulonephritis and systemic symptoms attributable to small vessel vasculitis. Although multisystemic manifestations are frequent, involvement of the gastrointestinal tract is uncommon. Cases have been reported of intestinal perforation, ulceration and hemorrhage. A patient whose initial presentation of Wegener’s granulomatosis was odynophagia secondary to esophageal vasculitis is described. Endoscopy revealed multiple punched out ulcerations in the esophagus, which resolved with standard therapy for systemic Wegener’s granulomatosis. There are only two previous reports of symptomatic esophageal vasculitis in patients with Wegener’s granulomatosis. These reports illustrate the need to consider odynophagia as a reflection of disease activity as opposed to complications of immunosuppressive therapy. |
| format | Article |
| id | doaj-art-fae63dc55bb848e091b82ccca417d83d |
| institution | Kabale University |
| issn | 0835-7900 |
| language | English |
| publishDate | 2000-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Gastroenterology |
| spelling | doaj-art-fae63dc55bb848e091b82ccca417d83d2025-02-03T01:04:18ZengWileyCanadian Journal of Gastroenterology0835-79002000-01-0114544945110.1155/2000/423569Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the LiteratureGlen A Fallows0Sean F Hamilton1Douglas S Taylor2S Bharati Reddy3St Clare’s Mercy Hospital, St John’s, Newfoundland, CanadaSt Clare’s Mercy Hospital, St John’s, Newfoundland, CanadaSt Clare’s Mercy Hospital, St John’s, Newfoundland, CanadaSt Clare’s Mercy Hospital, St John’s, Newfoundland, CanadaWegener’s granulomatosis is characterized by a granulomatous arteritis involving the upper and lower respiratory tracts, progressive glomerulonephritis and systemic symptoms attributable to small vessel vasculitis. Although multisystemic manifestations are frequent, involvement of the gastrointestinal tract is uncommon. Cases have been reported of intestinal perforation, ulceration and hemorrhage. A patient whose initial presentation of Wegener’s granulomatosis was odynophagia secondary to esophageal vasculitis is described. Endoscopy revealed multiple punched out ulcerations in the esophagus, which resolved with standard therapy for systemic Wegener’s granulomatosis. There are only two previous reports of symptomatic esophageal vasculitis in patients with Wegener’s granulomatosis. These reports illustrate the need to consider odynophagia as a reflection of disease activity as opposed to complications of immunosuppressive therapy.http://dx.doi.org/10.1155/2000/423569 |
| spellingShingle | Glen A Fallows Sean F Hamilton Douglas S Taylor S Bharati Reddy Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature Canadian Journal of Gastroenterology |
| title | Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature |
| title_full | Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature |
| title_fullStr | Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature |
| title_full_unstemmed | Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature |
| title_short | Esophageal Involvement in Wegener’s Granulomatosis: A Case Report and Review of the Literature |
| title_sort | esophageal involvement in wegener s granulomatosis a case report and review of the literature |
| url | http://dx.doi.org/10.1155/2000/423569 |
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