Chemoprotective effect of nimbolide against N-methyl-N-nitrosourea induced gastric cancer via alteration of apoptosis and NF-κB signaling pathway

Chemoprotective effect of nimbolide against N-methyl-N-nitrosourea induced gastric cancer via alteration of apoptosis and NF-κB signaling pathway

ABSTRACT Purpose: Gastric cancer (GC) ranks as the third most common cause of cancer related mortality and as the fifth most frequently diagnosed cancer globally. Less than 30% of people with GC survive for more than five years. Methods: Nimbolide has been shown to have anticancer, anti-inflammato...

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Bibliographic Details
Main Authors: Yizhong Gu, Binguo Liu, Xiaoting Xia, Chunlei Luo, Yi Ren
Format: Article
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2025-03-01
Series:Acta Cirúrgica Brasileira
Subjects:
Stomach Neoplasms
Antioxidants
Inflammation
Apoptosis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502025000100217&lng=en&tlng=en
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