Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study
Background: T-shaped uterus is a subclass of dysmorphic uteri according to the European Society of Human Reproductionand Embryology (ESHRE) classification. A T-shaped uterus might be related to poor reproductive outcomesor pregnancy complications. We aim to compare the success rates of in vitro fert...
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Royan Institute (ACECR), Tehran
2025-01-01
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| Series: | International Journal of Fertility and Sterility |
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| Online Access: | https://www.ijfs.ir/article_715034_db99eed86fdf6c1d7c7de6bab1704e10.pdf |
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| author | Fattaneh Pahlavan Shohreh Irani Mehri Mashayekhi Samira Vesali Fatemeh Niknejad Firoozeh Ahmadi Narges Bagheri-Lankarani |
| author_facet | Fattaneh Pahlavan Shohreh Irani Mehri Mashayekhi Samira Vesali Fatemeh Niknejad Firoozeh Ahmadi Narges Bagheri-Lankarani |
| author_sort | Fattaneh Pahlavan |
| collection | DOAJ |
| description | Background: T-shaped uterus is a subclass of dysmorphic uteri according to the European Society of Human Reproductionand Embryology (ESHRE) classification. A T-shaped uterus might be related to poor reproductive outcomesor pregnancy complications. We aim to compare the success rates of in vitro fertilization (IVF) between individualswith a normal uterus and those with a T-shaped uterus identified through Hysterosalpingography.Materials and Methods: A retrospective cohort study was done in Royan Institute, Iran, in April 2020-April 2021.In line with the criteria for inclusion and exclusion, 468 cases were selected. Inclusion criteria were as follow: womenof 20-45 years old, primary infertility, no repeated implantation failure (RIF), embryo quality “grade A” or “grade B”(freeze), and no consumption of smoking or alcohol. Patients with uterine fibroid, polyp, metabolic disorders, previousuterine surgery were excluded. Based on the hysterosalpingography (HSG) images, the patients were categorizedas: “T-shaped uterus” or “normal uterus”. IVF outcomes including positive or negative chemical pregnancy wereentered into SPSS software. Using the Chi-square test, the success rate of IVF in those groups was compared.Results: Of 468 cases, 91 cases had T-shaped uterus and 377 cases had normal uterus. The mean age of patients was34 ± 3. The frequency of positive chemical pregnancy in the T-shaped uterus group was 42.9%, but 48% in the normaluterus group. The distribution of positive clinical pregnancy was 34.06% in the T-shaped uterus group and 46.1% inthe normal uterus group. The distribution of failed pregnancies was 20.5% in women with T-shaped uteri and 19.8%in the normal uterus group (P=0.867). There was no significant difference observed between the two groups.Conclusion: The success rate of IVF and pregnancy outcomes of patients in the T-shape and normal groups were notfound to be statistically significantly different. |
| format | Article |
| id | doaj-art-fa7b93cba55b49b0bab8dae49ecf6b23 |
| institution | Kabale University |
| issn | 2008-076X 2008-0778 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Royan Institute (ACECR), Tehran |
| record_format | Article |
| series | International Journal of Fertility and Sterility |
| spelling | doaj-art-fa7b93cba55b49b0bab8dae49ecf6b232025-01-18T09:23:38ZengRoyan Institute (ACECR), TehranInternational Journal of Fertility and Sterility2008-076X2008-07782025-01-01191242810.22074/ijfs.2024.2007415.1497715034Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort StudyFattaneh Pahlavan0Shohreh Irani1Mehri Mashayekhi2Samira Vesali3Fatemeh Niknejad4Firoozeh Ahmadi5Narges Bagheri-Lankarani6Department of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Endocrinology and Female Infertility, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, IranDepartment of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Reproductive Imaging, Reproductive Biomedicine Research Center, Royan Institute for Reproductive Biomedicine, ACECR, Tehran, IranDepartment of Basic and Population Based Studies in NCD, Reproductive Epidemiology Research Center, Royan Institute, ACECR, Tehran, IranBackground: T-shaped uterus is a subclass of dysmorphic uteri according to the European Society of Human Reproductionand Embryology (ESHRE) classification. A T-shaped uterus might be related to poor reproductive outcomesor pregnancy complications. We aim to compare the success rates of in vitro fertilization (IVF) between individualswith a normal uterus and those with a T-shaped uterus identified through Hysterosalpingography.Materials and Methods: A retrospective cohort study was done in Royan Institute, Iran, in April 2020-April 2021.In line with the criteria for inclusion and exclusion, 468 cases were selected. Inclusion criteria were as follow: womenof 20-45 years old, primary infertility, no repeated implantation failure (RIF), embryo quality “grade A” or “grade B”(freeze), and no consumption of smoking or alcohol. Patients with uterine fibroid, polyp, metabolic disorders, previousuterine surgery were excluded. Based on the hysterosalpingography (HSG) images, the patients were categorizedas: “T-shaped uterus” or “normal uterus”. IVF outcomes including positive or negative chemical pregnancy wereentered into SPSS software. Using the Chi-square test, the success rate of IVF in those groups was compared.Results: Of 468 cases, 91 cases had T-shaped uterus and 377 cases had normal uterus. The mean age of patients was34 ± 3. The frequency of positive chemical pregnancy in the T-shaped uterus group was 42.9%, but 48% in the normaluterus group. The distribution of positive clinical pregnancy was 34.06% in the T-shaped uterus group and 46.1% inthe normal uterus group. The distribution of failed pregnancies was 20.5% in women with T-shaped uteri and 19.8%in the normal uterus group (P=0.867). There was no significant difference observed between the two groups.Conclusion: The success rate of IVF and pregnancy outcomes of patients in the T-shape and normal groups were notfound to be statistically significantly different.https://www.ijfs.ir/article_715034_db99eed86fdf6c1d7c7de6bab1704e10.pdfhysterosalpingographyinfertilityin vitro fertilizationurogenital abnormalitiesuterus |
| spellingShingle | Fattaneh Pahlavan Shohreh Irani Mehri Mashayekhi Samira Vesali Fatemeh Niknejad Firoozeh Ahmadi Narges Bagheri-Lankarani Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study International Journal of Fertility and Sterility hysterosalpingography infertility in vitro fertilization urogenital abnormalities uterus |
| title | Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study |
| title_full | Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study |
| title_fullStr | Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study |
| title_full_unstemmed | Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study |
| title_short | Comparison of In Vitro Fertilization Outcomes between Normal and T-Shaped Uteri, Diagnosed by Hysterosalpingography in Women with infertility: A Retrospective Cohort Study |
| title_sort | comparison of in vitro fertilization outcomes between normal and t shaped uteri diagnosed by hysterosalpingography in women with infertility a retrospective cohort study |
| topic | hysterosalpingography infertility in vitro fertilization urogenital abnormalities uterus |
| url | https://www.ijfs.ir/article_715034_db99eed86fdf6c1d7c7de6bab1704e10.pdf |
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