Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China
Objectives To evaluate the effect of hypertension and related comorbidities on the health-related quality of life (HRQoL) using EuroQol 5-dimensions instrument with five-level scale (EQ-5D-5L) Hong Kong (HK) version.Design Data were analysed by a secondary data analysis based on a cross-sectional st...
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BMJ Publishing Group
2019-09-01
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| Series: | BMJ Open |
| Online Access: | https://bmjopen.bmj.com/content/9/9/e032544.full |
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| author | Eliza Lai Yi Wong Richard Huan Xu Annie Wai Ling Cheung |
| author_facet | Eliza Lai Yi Wong Richard Huan Xu Annie Wai Ling Cheung |
| author_sort | Eliza Lai Yi Wong |
| collection | DOAJ |
| description | Objectives To evaluate the effect of hypertension and related comorbidities on the health-related quality of life (HRQoL) using EuroQol 5-dimensions instrument with five-level scale (EQ-5D-5L) Hong Kong (HK) version.Design Data were analysed by a secondary data analysis based on a cross-sectional study assessing experience on public specialist outpatient service.Setting A representative sample was recruited from 26 specialist outpatient clinics in HK.Participants A total of 4528 patients with hypertension aged 18 or above who responded to the survey.Intervention EQ-5D-5L HK was applied to assess the HRQoL. The five-dimension descriptive system and the utility index of EQ-5D-5L were treated as the dependent variable in the current study. Regression modelling was applied to estimate the effect of hypertension and related comorbidities on health-related quality of life.Results More respondents were women (53.9%), aged ≥65 years old (60.1%), and with primary educational attainment or below (52.3%). A total of 1466 respondents (32.4%) also reported suffering from diabetes, heart disease (20.8%), vision problem (1.7%) and cancer (1.5%). In the ordinal least squares model, utility decreased most when patients reported having physical disability associated with hypertension (beta=−0.395, SE=0.047), and 0.128, 0.064, 0.05 and 0.048 for mental problem, cancer, vision problem and heart problem. In the Tobit model, the utility reduced most for comorbidity of physical disability, and then mental problem, cancer, vision problem, heart problem and diabetes. For first part of two-part model, respondents coliving with mental problem were 10% less likely to report a full health. For the second part of two-part model, the respondents with physical disability had 0.294 lower in utility.Conclusions Respondents with hypertension reported a low EQ-5D utility score. Respondents were women, with a high education, fully employed and living with families reported better HRQoL. There is a significant effect of comorbidity influence on the decreased HRQoL, particularly those with physical disability and mental problem. |
| format | Article |
| id | doaj-art-fa77f3b2aaed4b00bd101e6cd1fe7d7a |
| institution | OA Journals |
| issn | 2044-6055 |
| language | English |
| publishDate | 2019-09-01 |
| publisher | BMJ Publishing Group |
| record_format | Article |
| series | BMJ Open |
| spelling | doaj-art-fa77f3b2aaed4b00bd101e6cd1fe7d7a2025-08-20T01:54:12ZengBMJ Publishing GroupBMJ Open2044-60552019-09-019910.1136/bmjopen-2019-032544Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, ChinaEliza Lai Yi Wong0Richard Huan Xu1Annie Wai Ling Cheung2Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, ChinaCentre for Health Systems and Policy Research, Jockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, ChinaJockey Club School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong SAR, ChinaObjectives To evaluate the effect of hypertension and related comorbidities on the health-related quality of life (HRQoL) using EuroQol 5-dimensions instrument with five-level scale (EQ-5D-5L) Hong Kong (HK) version.Design Data were analysed by a secondary data analysis based on a cross-sectional study assessing experience on public specialist outpatient service.Setting A representative sample was recruited from 26 specialist outpatient clinics in HK.Participants A total of 4528 patients with hypertension aged 18 or above who responded to the survey.Intervention EQ-5D-5L HK was applied to assess the HRQoL. The five-dimension descriptive system and the utility index of EQ-5D-5L were treated as the dependent variable in the current study. Regression modelling was applied to estimate the effect of hypertension and related comorbidities on health-related quality of life.Results More respondents were women (53.9%), aged ≥65 years old (60.1%), and with primary educational attainment or below (52.3%). A total of 1466 respondents (32.4%) also reported suffering from diabetes, heart disease (20.8%), vision problem (1.7%) and cancer (1.5%). In the ordinal least squares model, utility decreased most when patients reported having physical disability associated with hypertension (beta=−0.395, SE=0.047), and 0.128, 0.064, 0.05 and 0.048 for mental problem, cancer, vision problem and heart problem. In the Tobit model, the utility reduced most for comorbidity of physical disability, and then mental problem, cancer, vision problem, heart problem and diabetes. For first part of two-part model, respondents coliving with mental problem were 10% less likely to report a full health. For the second part of two-part model, the respondents with physical disability had 0.294 lower in utility.Conclusions Respondents with hypertension reported a low EQ-5D utility score. Respondents were women, with a high education, fully employed and living with families reported better HRQoL. There is a significant effect of comorbidity influence on the decreased HRQoL, particularly those with physical disability and mental problem.https://bmjopen.bmj.com/content/9/9/e032544.full |
| spellingShingle | Eliza Lai Yi Wong Richard Huan Xu Annie Wai Ling Cheung Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China BMJ Open |
| title | Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China |
| title_full | Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China |
| title_fullStr | Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China |
| title_full_unstemmed | Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China |
| title_short | Health-related quality of life among patients with hypertension: population-based survey using EQ-5D-5L in Hong Kong SAR, China |
| title_sort | health related quality of life among patients with hypertension population based survey using eq 5d 5l in hong kong sar china |
| url | https://bmjopen.bmj.com/content/9/9/e032544.full |
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