Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement
The occurrence of extranodal primary B cell non-Hodgkin’s lymphoma is rare. Total hip replacement is one of the most common orthopaedic procedures performed. There has been an increased incidence of primary lymphomas involving periprosthetic sites. Chronic inflammation due to metal debris arising fr...
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| Format: | Article |
| Language: | English |
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Wiley
2017-01-01
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| Series: | Case Reports in Orthopedics |
| Online Access: | http://dx.doi.org/10.1155/2017/7195016 |
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| author | Aysha Rajeev Angela Ralte Nameer Choudhry Faizan Jabbar Paul Banaszkiewicz |
| author_facet | Aysha Rajeev Angela Ralte Nameer Choudhry Faizan Jabbar Paul Banaszkiewicz |
| author_sort | Aysha Rajeev |
| collection | DOAJ |
| description | The occurrence of extranodal primary B cell non-Hodgkin’s lymphoma is rare. Total hip replacement is one of the most common orthopaedic procedures performed. There has been an increased incidence of primary lymphomas involving periprosthetic sites. Chronic inflammation due to metal debris arising from the prosthetic implants has been evidenced as one of the causes for the development of soft tissue lymphomas albeit rarely. We describe a case report of a 77-year-old patient who had underwent a cemented total hip replacement in the past who further developed large B cell primary non-Hodgkin’s lymphoma. She presented initially with signs and symptoms highly suggestive of underlying periprosthetic infection. The radiological imaging was also indicative of periprosthetic infection. The diagnosis was eventually confirmed after an open biopsy. This case underlines the importance of considering and including soft tissue malignancy in the differential diagnosis of suspected chronic periprosthetic infection. |
| format | Article |
| id | doaj-art-fa73b4ccd88f49609b4ce585fd60bced |
| institution | Kabale University |
| issn | 2090-6749 2090-6757 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Orthopedics |
| spelling | doaj-art-fa73b4ccd88f49609b4ce585fd60bced2025-02-03T06:01:27ZengWileyCase Reports in Orthopedics2090-67492090-67572017-01-01201710.1155/2017/71950167195016Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip ReplacementAysha Rajeev0Angela Ralte1Nameer Choudhry2Faizan Jabbar3Paul Banaszkiewicz4Department of Trauma and Orthopaedics, Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Sheriff Hill, Gateshead NE9 6SX, UKDepartment of Pathology, Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Sheriff Hill, Gateshead NE9 6SX, UKDepartment of Trauma and Orthopaedics, Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Sheriff Hill, Gateshead NE9 6SX, UKDepartment of Trauma and Orthopaedics, Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Sheriff Hill, Gateshead NE9 6SX, UKDepartment of Trauma and Orthopaedics, Queen Elizabeth Hospital, Gateshead Health NHS Foundation Trust, Sheriff Hill, Gateshead NE9 6SX, UKThe occurrence of extranodal primary B cell non-Hodgkin’s lymphoma is rare. Total hip replacement is one of the most common orthopaedic procedures performed. There has been an increased incidence of primary lymphomas involving periprosthetic sites. Chronic inflammation due to metal debris arising from the prosthetic implants has been evidenced as one of the causes for the development of soft tissue lymphomas albeit rarely. We describe a case report of a 77-year-old patient who had underwent a cemented total hip replacement in the past who further developed large B cell primary non-Hodgkin’s lymphoma. She presented initially with signs and symptoms highly suggestive of underlying periprosthetic infection. The radiological imaging was also indicative of periprosthetic infection. The diagnosis was eventually confirmed after an open biopsy. This case underlines the importance of considering and including soft tissue malignancy in the differential diagnosis of suspected chronic periprosthetic infection.http://dx.doi.org/10.1155/2017/7195016 |
| spellingShingle | Aysha Rajeev Angela Ralte Nameer Choudhry Faizan Jabbar Paul Banaszkiewicz Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement Case Reports in Orthopedics |
| title | Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement |
| title_full | Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement |
| title_fullStr | Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement |
| title_full_unstemmed | Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement |
| title_short | Diffuse B Cell Non-Hodgkin’s Lymphoma Presenting Atypically as Periprosthetic Joint Infection in a Total Hip Replacement |
| title_sort | diffuse b cell non hodgkin s lymphoma presenting atypically as periprosthetic joint infection in a total hip replacement |
| url | http://dx.doi.org/10.1155/2017/7195016 |
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