High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1
Objective. To estimate HPV prevalence among pregnant women from Ribeirão Preto, Brazil, and the possible influence of HIV-1 infection on this prevalence. Methods. A cross-sectional study with 44 HIV-positive and 53 HIV-negative pregnant women was conducted. Cervicovaginal specimens were obtained fro...
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| Format: | Article |
| Language: | English |
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Wiley
2009-01-01
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| Series: | Obstetrics and Gynecology International |
| Online Access: | http://dx.doi.org/10.1155/2009/485423 |
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| author | Emilia Moreira Jalil Geraldo Duarte Patrícia El Beitune Renata Toscano Simões Patrícia Pereira dos Santos Melli Silvana Maria Quintana |
| author_facet | Emilia Moreira Jalil Geraldo Duarte Patrícia El Beitune Renata Toscano Simões Patrícia Pereira dos Santos Melli Silvana Maria Quintana |
| author_sort | Emilia Moreira Jalil |
| collection | DOAJ |
| description | Objective. To estimate HPV prevalence among pregnant women from Ribeirão Preto, Brazil, and the possible influence of HIV-1 infection on this prevalence. Methods. A cross-sectional study with 44 HIV-positive and 53 HIV-negative pregnant women was conducted. Cervicovaginal specimens were obtained from all women during gynecologic exam. HPV DNA, low and high risk HPV types, was detected using conventional PCR. Statistical analysis used Student's t-test, Mann-Whitney test, Fischer's Exact test, and prevalence ratios with 95% confidence interval. Results. HIV-positive pregnant women had higher proportion of HPV infection than HIV-negative pregnant women (79.5% versus 58.5%; P<.05). HPV positivity prevalence ratio for HIV-positive women was 1.36 (95% CI 1.04–1.8; P=.03). There was significant association between HIV viral load levels and HPV positivity (P<.05). Conclusions. Our results demonstrate higher HPV positivity in HIV-infected pregnant women. Higher values of HIV viral load were associated with HPV positivity. |
| format | Article |
| id | doaj-art-fa6e2a2ac58448b8bc5ae2a41d090d63 |
| institution | Kabale University |
| issn | 1687-9589 1687-9597 |
| language | English |
| publishDate | 2009-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Obstetrics and Gynecology International |
| spelling | doaj-art-fa6e2a2ac58448b8bc5ae2a41d090d632025-02-03T05:44:39ZengWileyObstetrics and Gynecology International1687-95891687-95972009-01-01200910.1155/2009/485423485423High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1Emilia Moreira Jalil0Geraldo Duarte1Patrícia El Beitune2Renata Toscano Simões3Patrícia Pereira dos Santos Melli4Silvana Maria Quintana5STD Unit, Brazilian Program of STD/Aids, Secretariat for Health Surveillance, Ministry of Health, 70070-600 Brasília, DF, BrazilDepartment of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 14049-900 Ribeirão Preto, SP, BrazilDepartment of Obstetrics and Gynecology, Medical School of the Federal University of Health Sciences of Porto Alegre, 90020-090 Porto Alegre, RS, BrazilDepartment of Medicine, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 30150-221 Ribeirão Preto, SP, BrazilDepartment of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 14049-900 Ribeirão Preto, SP, BrazilDepartment of Gynecology and Obstetrics, Faculty of Medicine of Ribeirão Preto, University of São Paulo, 14049-900 Ribeirão Preto, SP, BrazilObjective. To estimate HPV prevalence among pregnant women from Ribeirão Preto, Brazil, and the possible influence of HIV-1 infection on this prevalence. Methods. A cross-sectional study with 44 HIV-positive and 53 HIV-negative pregnant women was conducted. Cervicovaginal specimens were obtained from all women during gynecologic exam. HPV DNA, low and high risk HPV types, was detected using conventional PCR. Statistical analysis used Student's t-test, Mann-Whitney test, Fischer's Exact test, and prevalence ratios with 95% confidence interval. Results. HIV-positive pregnant women had higher proportion of HPV infection than HIV-negative pregnant women (79.5% versus 58.5%; P<.05). HPV positivity prevalence ratio for HIV-positive women was 1.36 (95% CI 1.04–1.8; P=.03). There was significant association between HIV viral load levels and HPV positivity (P<.05). Conclusions. Our results demonstrate higher HPV positivity in HIV-infected pregnant women. Higher values of HIV viral load were associated with HPV positivity.http://dx.doi.org/10.1155/2009/485423 |
| spellingShingle | Emilia Moreira Jalil Geraldo Duarte Patrícia El Beitune Renata Toscano Simões Patrícia Pereira dos Santos Melli Silvana Maria Quintana High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1 Obstetrics and Gynecology International |
| title | High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1 |
| title_full | High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1 |
| title_fullStr | High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1 |
| title_full_unstemmed | High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1 |
| title_short | High Prevalence of Human Papillomavirus Infection among Brazilian Pregnant Women with and without Human Immunodeficiency Virus Type 1 |
| title_sort | high prevalence of human papillomavirus infection among brazilian pregnant women with and without human immunodeficiency virus type 1 |
| url | http://dx.doi.org/10.1155/2009/485423 |
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